Dunbar Grace E, Shen Bailey Yuguan, Aref Ahmad A
Illinois Eye and Ear Infirmary, Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Clin Ophthalmol. 2017 May 8;11:875-882. doi: 10.2147/OPTH.S109708. eCollection 2017.
Intraocular pressure, a major modifiable risk factor for glaucoma, has been shown to fluctuate throughout the day in patients with glaucoma. The detection and measurement of this fluctuation may help guide the clinical management of glaucomatous individuals. The Sensimed Triggerfish contact lens sensor (CLS), which has recently gained approval for marketing in the USA, is designed to detect intraocular pressure-related changes in an eye over a 24-hour period. This review will provide an overview of the Triggerfish CLS, as well as summarize current clinical data pertaining to the device. Overall, the current evidence suggests that the Triggerfish CLS is safe and well tolerated, and provides reproducible results. One challenge of using the Triggerfish CLS is that it may only provide data on relative changes in intraocular pressure rather than absolute intraocular pressure. In addition, its validity at estimating intraocular pressure compared to other methods is still controversial. Despite these limitations, recent studies suggest a myriad of potential indications for the Triggerfish CLS, including predicting glaucomatous progression and predicting efficacy of glaucoma treatment. With further research, the Triggerfish CLS may become a useful tool for eye care practitioners.
眼压是青光眼的一个主要可改变风险因素,研究表明青光眼患者的眼压在一天中会波动。检测和测量这种波动可能有助于指导青光眼患者的临床管理。最近在美国获得上市批准的Sensimed Triggerfish隐形眼镜传感器(CLS)旨在检测眼睛在24小时内与眼压相关的变化。本综述将概述Triggerfish CLS,并总结与该设备相关的当前临床数据。总体而言,目前的证据表明Triggerfish CLS安全且耐受性良好,并能提供可重复的结果。使用Triggerfish CLS的一个挑战是它可能只提供眼压相对变化的数据,而不是绝对眼压。此外,与其他方法相比,其在估计眼压方面的有效性仍存在争议。尽管有这些局限性,但最近的研究表明Triggerfish CLS有许多潜在的应用指征,包括预测青光眼进展和预测青光眼治疗效果。随着进一步研究,Triggerfish CLS可能会成为眼科护理从业者的一个有用工具。