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三种台湾特有龙胆属物种与中国药用植物龙胆的比较分析。

Comparative analysis among three Taiwan-specific Gentiana species and Chinese medicinal plant Gentiana scabra.

作者信息

Huang Shih-Hung, Chen Emily Hin-Fun, Wu Chin-Tung, Kuo Chao-Lin, Tsay Hsin-Sheng

机构信息

Department of Applied Chemistry, Chaoyang University of Technology, Taichung, Taiwan.

Department of Computer Science and Information Engineering, Providence University, Taichung, Taiwan.

出版信息

Bot Stud. 2013 Dec;54(1):54. doi: 10.1186/1999-3110-54-54. Epub 2013 Nov 5.

DOI:10.1186/1999-3110-54-54
PMID:28510889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5430382/
Abstract

BACKGROUND

The root of Gentiana scabra is commonly known as Longdan in Chinese herbal medicines and has been used in the treatment of inflammation, anorexia, indigestion and gastric infections for over 2000 years. High market demand had made G. scabra (GS) plants not to be the only source of Longdan in China, other Gentiana spp., G. triflora, G. manshurica and G. rigescens, were also recognized as Longdan in China now.

RESULTS

In this study, we identified three Taiwan-specific Gentiana spp., G. davidii var. formosana (GDF) and G. arisanensis (GA) and G. scabrida var. punctulata (GSP) that are phylogenetically different from GS (main source of Longdan). However, the active compounds of Longdan, gentiopicroside and swertiamari, were found in GSP and GDF showed higher antioxidant ability and free radical scavenging activities than Chinese Longdan. This discovery might explore the medicinal potential of GDF. Meanwhile, another Taiwan-specific Gentiana spp., GSP, was found to have the strongest antioxidant ability and free radical scavenging activities which might suggest a possible use of GSP as a source of natural antioxidant agents for industrial purpose.

CONCLUSIONS

The finding of this study indicated that ITS analysis can be used to identify Taiwan-specific Gentiana spp. Also the Taiwan-specific Gentiana spp. which has strongest antioxidant and free radical scavenging activities among others could be a better choice for industrial purpose.

摘要

背景

龙胆草的根在中药材中通常被称为龙胆,已被用于治疗炎症、食欲不振、消化不良和胃部感染达2000多年。市场需求旺盛使得龙胆草属植物不再是中国龙胆的唯一来源,其他龙胆属植物,如三花龙胆、条叶龙胆和坚龙胆,现在在中国也被认定为龙胆。

结果

在本研究中,我们鉴定出三种台湾特有的龙胆属植物,即台湾龙胆、阿里山龙胆和点叶龙胆,它们在系统发育上与龙胆草(龙胆的主要来源)不同。然而,在点叶龙胆中发现了龙胆的活性成分龙胆苦苷和獐牙菜苷,并且台湾龙胆显示出比中国龙胆更高的抗氧化能力和自由基清除活性。这一发现可能会挖掘台湾龙胆的药用潜力。同时,另一种台湾特有的龙胆属植物,点叶龙胆,被发现具有最强的抗氧化能力和自由基清除活性,这可能表明点叶龙胆有可能作为工业用天然抗氧化剂的来源。

结论

本研究结果表明,ITS分析可用于鉴定台湾特有的龙胆属植物。此外,在台湾特有的龙胆属植物中,具有最强抗氧化和自由基清除活性的植物可能是工业用途的更好选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/a150035a06cc/40529_2013_Article_46_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/0f3c5f5da82c/40529_2013_Article_46_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/56cc5dc79f48/40529_2013_Article_46_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/eea4fcb48553/40529_2013_Article_46_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/6e5807a4ad18/40529_2013_Article_46_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/a150035a06cc/40529_2013_Article_46_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/0f3c5f5da82c/40529_2013_Article_46_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/56cc5dc79f48/40529_2013_Article_46_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/eea4fcb48553/40529_2013_Article_46_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/6e5807a4ad18/40529_2013_Article_46_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/5430382/a150035a06cc/40529_2013_Article_46_Fig5_HTML.jpg

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