Department of Orthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, and Beijing Key Laboratory of Digital Stomatology, Peking University , 22 Zhongguancun South Avenue, Haidian District, Beijing 100081, P. R. China.
State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and Department of Chemistry, Lanzhou University , Lanzhou 730000, P. R. China.
ACS Appl Mater Interfaces. 2017 May 31;9(21):17688-17692. doi: 10.1021/acsami.7b05284. Epub 2017 May 22.
Dental materials often cause bacterial adhesion and promote bacterial biofilm formation, which brings a series of long-standing and significant problems in oral health. However, the current development of antibacterial research in dental devices is limited by the lack of materials endowed with good antibacterial properties against oral bacteria. Here, we present a new strategy for reducing the initial adhesion of bacterial on dental biomaterials by chemically bonding long-chain polyethylene glycol. Our work represents an important step toward solving the problem of bacterial accumulation on dental devices.
牙科材料通常会导致细菌黏附，并促进细菌生物膜的形成，这给口腔健康带来了一系列长期且重大的问题。然而，目前牙科器械的抗菌研究进展受到限制，原因是缺乏具有良好抗口腔细菌性能的材料。在这里，我们提出了一种通过化学键合长链聚乙二醇来减少牙科生物材料上细菌初始黏附的新策略。我们的工作为解决牙科器械上细菌堆积问题迈出了重要的一步。
