Galdiero F, Gorga F, Bentivoglio C, Mancuso R, Galdiero E, Tufano M A
Istituto di Microbiologia, I Facoltà di Medicina e Chirurgia Università di Napoli.
Infection. 1988;16(6):349-53. doi: 10.1007/BF01644545.
This study examines the action of the cell wall components of enterobacteria on the vitality of human spermatozoa. Lipopolysaccharides extracted from Escherichia coli K12 killed about 80% of the spermatozoa at a concentration of 50 micrograms/ml. Porins extracted from E. coli, Proteus mirabilis and Salmonella typhimurium killed between 80% and 100% of the spermatozoa at a concentration of 50 micrograms/ml. Muramic acid and N-acetylmuramic acid caused about 60% mortality at a concentration of 50 micrograms/ml. The possibility that the products of cellular lysis in the course of gram-negative infections cause temporary sterility is discussed.
本研究考察了肠杆菌细胞壁成分对人类精子活力的作用。从大肠杆菌K12中提取的脂多糖在浓度为50微克/毫升时可杀死约80%的精子。从大肠杆菌、奇异变形杆菌和鼠伤寒沙门氏菌中提取的孔蛋白在浓度为50微克/毫升时可杀死80%至100%的精子。胞壁酸和N - 乙酰胞壁酸在浓度为50微克/毫升时可导致约60%的死亡率。文中讨论了革兰氏阴性菌感染过程中细胞裂解产物导致暂时不育的可能性。
