Im Hee-Jin, Baek Shin-Hye, Chu Min Kyung, Yang Kwang Ik, Kim Won-Joo, Park Seong-Ho, Thomas Robert J, Yun Chang-Ho
Department of Neurology, Korea University Anam Hospital, Seoul, Republic of Korea.
Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Sleep. 2017 Jul 1;40(7). doi: 10.1093/sleep/zsx089.
To determine if weekend catch-up sleep (CUS) impacts body mass index (BMI) in the general population.
A stratified random sample (2156 subjects; age 19-82 years old, 43.0 ± 14.5; 1183 male) from the general population was evaluated, in 2010, using face-to-face interviews about sociodemographic characteristics, height, weight, habitual sleep duration, and time-in-bed at night on weekdays and weekend, sleep-related profiles, mood and anxiety scales, and comorbid-medical conditions. Weekend CUS was identified when nocturnal sleep extension occurred over the weekend, and this was quantified. Average sleep duration, BMI, and chronotype were determined. The association of BMI with the presence and the amount of weekend CUS was analyzed, independent of average sleep duration, chronotype, and sociodemographic factors.
BMI and average sleep duration was 23.0 ± 3.0 kg/m2 and 7.3 ± 1.2 hours, respectively. The weekend CUS group consisted of 932 subjects (43.2%) who slept longer on weekend than weekdays by 1.8 ± 1.1 hours. Weekend CUS subjects had a significantly lower BMI (22.8 ± 0.19 kg/m2) than the non-CUS (23.1 ± 0.19 kg/m2) group, after adjustment for age, sex, average sleep duration, chronotype, other sociodemographic factors, and anxiety/mood status (p = .01) The relationship between weekend CUS and BMI was dose-dependent (p = 0.02): Every additional hour of weekend CUS was associated with a decrease of 0.12 kg/m2 in BMI (95% confidence interval, -0.23 to -0.02).
Weekend sleep extension may have biological protective effects in preventing sleep-restriction induced or related obesity. The results suggest a simple population-level strategy to minimize effects of sleep loss.
确定周末补觉（CUS）是否会影响普通人群的体重指数（BMI）。
2010年，对来自普通人群的分层随机样本（2156名受试者；年龄19 - 82岁，43.0±14.5；1183名男性）进行评估，通过面对面访谈了解其社会人口学特征、身高、体重、习惯性睡眠时间、工作日和周末夜间卧床时间、睡眠相关情况、情绪和焦虑量表以及合并症。当周末夜间睡眠时间延长时确定为周末CUS，并对其进行量化。确定平均睡眠时间、BMI和昼夜节律类型。分析BMI与周末CUS的存在及量之间的关联，独立于平均睡眠时间、昼夜节律类型和社会人口学因素。
BMI和平均睡眠时间分别为23.0±3.0kg/m²和7.3±1.2小时。周末CUS组由932名受试者（43.2%）组成，他们周末的睡眠时间比工作日长1.8±1.1小时。在调整年龄、性别、平均睡眠时间、昼夜节律类型、其他社会人口学因素以及焦虑/情绪状态后，周末CUS受试者的BMI（22.8±0.19kg/m²）显著低于非CUS组（23.1±0.19kg/m²）（p = 0.01）。周末CUS与BMI之间的关系呈剂量依赖性（p = 0.02）：周末CUS每增加一小时，BMI降低0.12kg/m²（95%置信区间，-0.23至-0.02）。
周末延长睡眠时间可能对预防睡眠限制引起的或与之相关的肥胖具有生物学保护作用。研究结果提示了一种简单的人群层面策略，以尽量减少睡眠不足的影响。
