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牛津髋关节评分西班牙语版在髋骨关节炎患者中的跨文化适应与验证

Cross-cultural adaptation and validation of the Spanish version of the Oxford Hip Score in patients with hip osteoarthritis.

作者信息

Martín-Fernández Jesús, Gray-Laymón Pedro, Molina-Siguero Antonio, Martínez-Martín Javier, García-Maroto Roberto, García-Sánchez Isidoro, García-Pérez Lidia, Ramos-García Vanesa, Castro-Casas Olga, Bilbao Amaia

机构信息

C° Villamanta (C.S. Navalcarnero). Gerencia Asistencial de Atención Primaria. Servicio Madrileño de Salud, Madrid, Spain.

Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos, Madrid, Spain.

出版信息

BMC Musculoskelet Disord. 2017 May 22;18(1):205. doi: 10.1186/s12891-017-1568-3.

Abstract

BACKGROUND

Osteoarthritis (OA) of the hip is a disease that entails a major burden for patients and the society as a whole. One way of measuring this burden for the patient is through impact on Health-related Quality of Life (HRQL). The Oxford Hip Score (OHS) is a well-known tool to measure HRQL in patients with OA of the hip. This study aims to assess the psychometric properties of the Spanish-adapted version of the OHS, including its reliability, validity, and sensitivity to change.

METHODS

Prospective observational study that included 361 patients diagnosed with hip OA (according to the criterion of the American College of Rheumatology) from 3 different Spanish regions. Their HRQL was assessed using a generic questionnaire, the EQ-5D-5 L, and two specific ones (the Western Ontario and McMaster Universities Osteoarthritis Index, WOMAC, and the OHS) adapted to Spanish. There was a follow-up period of 6 months, and the acceptability, psychometric properties, presence of ceiling and floor effects, validity, reliability, and sensitivity to changes of the OHS were measured.

RESULTS

The OHS was fully answered in 99.4% of cases with no indication of ceiling or floor effects. Its factor structure can be explained in a single dimension. Its discriminative capacity was very good compared to the groups generated by the WOMAC and the EQ-5D-5 L. The correlation between the OHS and dimensions of the WOMAC or EQ-5D-5 L utilities was ≥0.7. Excellent test-retest reliability (ICC = 0.992; CI95%: 0.994-0.998) and internal consistency (Cronbach's α = 0.928) were observed. The minimal clinically important difference (MCID) was 7.0 points, and the minimum detectable change (MDC) was 5.5 points. The effect size for moderate improvement in perceived HRQL was 0.73, similar to that of WOMAC dimensions and higher than the EQ-5D-5 L.

CONCLUSIONS

The Spanish-adapted version of the OHS is a useful, acceptable tool for the assessment of perceived HRQL in patients with hip OA, and has psychometric properties similar to those of the WOMAC that allow for discriminating both a patient's condition at a given moment and changes that can occur over time.

摘要

背景

髋关节骨关节炎(OA)是一种给患者乃至整个社会带来沉重负担的疾病。衡量患者所承受负担的一种方法是通过对健康相关生活质量(HRQL)的影响。牛津髋关节评分(OHS)是一种用于测量髋关节OA患者HRQL的知名工具。本研究旨在评估OHS西班牙文改编版的心理测量特性,包括其信度、效度和对变化的敏感性。

方法

前瞻性观察性研究,纳入了来自西班牙3个不同地区的361例诊断为髋关节OA(根据美国风湿病学会标准)的患者。使用一份通用问卷EQ-5D-5L以及两份翻译成西班牙文的特定问卷(西安大略和麦克马斯特大学骨关节炎指数,WOMAC,以及OHS)对他们的HRQL进行评估。随访期为6个月,测量OHS的可接受性、心理测量特性、天花板效应和地板效应的存在情况、效度、信度以及对变化的敏感性。

结果

99.4%的病例完整回答了OHS,无天花板效应或地板效应迹象。其因子结构可用单一维度解释。与WOMAC和EQ-5D-5L产生的分组相比,其区分能力非常好。OHS与WOMAC维度或EQ-5D-5L效用之间的相关性≥0.7。观察到了出色的重测信度(ICC = 0.992;95%CI:0.994 - 0.998)和内部一致性(Cronbach'sα = 0.928)。最小临床重要差异(MCID)为7.0分,最小可检测变化(MDC)为5.5分。感知HRQL中度改善的效应大小为0.73,与WOMAC维度相似且高于EQ-5D-5L。

结论

OHS西班牙文改编版是评估髋关节OA患者感知HRQL的一种有用且可接受的工具,其心理测量特性与WOMAC相似,能够区分患者在特定时刻的状况以及随时间可能发生的变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bce0/5440982/6861fb977142/12891_2017_1568_Fig1_HTML.jpg

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