Laboratoire de Virologie EA3610, CHU de Lille, Faculté de Médecine, Université de Lille, Lille, France.
Intervirology. 2018;61(5):205-213. doi: 10.1159/000448807. Epub 2017 Jun 15.
Human enteric viruses are associated with several clinical features, especially gastroenteritis. Large amounts of these viruses can be released in the environment and spread to people. Enteric viruses are nonenveloped viruses and have displayed good survival in the environment. They can be significantly resistant in food and water but also on fomites, and this is thought to play a role in transmission, leading to sporadic cases or outbreaks. The survival of enteric viruses on fomites relies on many factors including the virus itself, fomite properties, and extrinsic environmental factors such as temperature or relative humidity. Several reports in the literature have found an association with gastroenteritis cases or outbreaks and fomites naturally contaminated by enteric viruses. However, the study of virus survival following natural contamination is challenging, and most published studies are laboratory based, using experimental contamination. In addition, recent and detailed data on the resistance of each of the main enteric viruses on fomites are scarce. Many approaches, both physical and chemical, can be used to inactivate enteric viruses, the efficacy of which depends on the virus and the disinfection conditions.
人类肠道病毒与多种临床特征有关,尤其是肠胃炎。大量的肠道病毒可以在环境中释放,并传播给人类。肠道病毒是非包膜病毒,在环境中具有良好的生存能力。它们在食物和水中具有很强的抵抗力,但在污染物上也有一定的抵抗力,这被认为在传播中起作用,导致散发病例或暴发。肠道病毒在污染物上的存活取决于许多因素,包括病毒本身、污染物特性以及环境中的外部因素,如温度或相对湿度。文献中有几篇报道发现肠道病毒与肠胃炎病例或暴发以及被肠道病毒自然污染的污染物之间存在关联。然而,对自然污染后病毒存活情况的研究具有挑战性,并且大多数已发表的研究都是基于实验室的,使用实验性污染。此外,关于每种主要肠道病毒在污染物上的抵抗力的最新和详细数据非常缺乏。许多物理和化学方法都可用于灭活肠道病毒,其效果取决于病毒和消毒条件。