Gasim Gasim I, Elmugabil Abdelmageed, Hamdan Hamdan Z, Rayis Duria A, Adam Ishag
Faculty of Medicine, Al-Neelain University, Khartoum.
Faculty of Medicine, El Imam El Mahdi University, Kosti.
Clin Pract. 2017 Jun 7;7(3):958. doi: 10.4081/cp.2017.958.
The objective was to investigate the prevalence and the association between blood groups and IgG seropositivity among pregnant Sudanese women. A cross-sectional survey was carried-out at Saad Abul Ela Maternity Hospital, Khartoum, Sudan during the period of July 2014 through December 2015. Questionnaires covering socio-demographic and obstetrics information were administered. Specific IgG antibody was analysed using ELISA. One hundred eighty six pregnant women were enrolled. The mean (SD) of the age, parity was 28.3 (2.6) years and 2.6 (3.5), respectively. Of the 186 women, 42 (22.6%), 24 (12.9%), 11(5.9%) and 109 (58.6%) had blood group A, B, AB and O, respectively. IgG seropositivity rate was 132/186 (71.0%). There was no significant difference in age and parity between women with IgG seropositive and seronegative. Compared with the women with IgG seronegative, significantly higher numbers of women with IgG seropositive had O blood group, [84/132(63.6) 25/54(46.3), P<0.001]. In binary logistic regression, women with O blood group (OR= 2.084, 95% CI=1.060-4.097, P=0.033) were at a higher IgG seropositivity. The current study showed that women with blood group O were at higher risk for IgG seropositivity.
目的是调查苏丹孕妇中血型与IgG血清阳性率之间的患病率及关联。2014年7月至2015年12月期间，在苏丹喀土穆的萨阿德·阿布勒·埃拉妇产医院进行了一项横断面调查。发放了涵盖社会人口统计学和产科信息的问卷。使用酶联免疫吸附测定法分析特异性IgG抗体。共纳入186名孕妇。年龄和产次的均值（标准差）分别为28.3（2.6）岁和2.6（3.5）。在这186名女性中，分别有42名（22.6%）、24名（12.9%）、11名（5.9%）和109名（58.6%）的血型为A、B、AB和O型。IgG血清阳性率为132/186（71.0%）。IgG血清阳性和血清阴性的女性在年龄和产次上无显著差异。与IgG血清阴性的女性相比，IgG血清阳性的女性中血型为O型的人数显著更多，[84/132（63.6）对25/54（46.3），P<0.001]。在二元逻辑回归中，血型为O型的女性（比值比=2.084，95%置信区间=1.060 - 4.097，P=0.033）IgG血清阳性的风险更高。当前研究表明，血型为O型的女性IgG血清阳性的风险更高。
