O Blood Group as a Risk Factor for IgG Seropositivity Among Pregnant Sudanese Women.

The objective was to investigate the prevalence and the association between blood groups and IgG seropositivity among pregnant Sudanese women. A cross-sectional survey was carried-out at Saad Abul Ela Maternity Hospital, Khartoum, Sudan during the period of July 2014 through December 2015. Questionnaires covering socio-demographic and obstetrics information were administered. Specific IgG antibody was analysed using ELISA. One hundred eighty six pregnant women were enrolled. The mean (SD) of the age, parity was 28.3 (2.6) years and 2.6 (3.5), respectively. Of the 186 women, 42 (22.6%), 24 (12.9%), 11(5.9%) and 109 (58.6%) had blood group A, B, AB and O, respectively. IgG seropositivity rate was 132/186 (71.0%). There was no significant difference in age and parity between women with IgG seropositive and seronegative. Compared with the women with IgG seronegative, significantly higher numbers of women with IgG seropositive had O blood group, [84/132(63.6) 25/54(46.3), P<0.001]. In binary logistic regression, women with O blood group (OR= 2.084, 95% CI=1.060-4.097, P=0.033) were at a higher IgG seropositivity. The current study showed that women with blood group O were at higher risk for IgG seropositivity.