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因急性细支气管炎住院的儿童病毒性呼吸道感染的病因、季节性和临床特征:一项单中心研究

Etiology, Seasonality, and Clinical Features of Viral Respiratory Tract Infections in Children Hospitalized With Acute Bronchiolitis: A Single-Center Study.

作者信息

Gökçe Şule, Kurugöl Zafer, Koturoğlu Güldane, Çiçek Candan, Aslan Aslı

机构信息

Ege University, Bornova, Izmir, Turkey.

出版信息

Glob Pediatr Health. 2017 Jun 22;4:2333794X17714378. doi: 10.1177/2333794X17714378. eCollection 2017.

Abstract

The purpose of this study was to evaluate the viral frequency, seasonality, and clinical and demographic features of patients hospitalized with acute bronchiolitis. A cross-sectional, descriptive study was performed in 316 infants younger than 2 years of age who were hospitalized for acute viral bronchiolitis. Respiratory tract infection agents were investigated with polymerase chain reaction (PCR). A total of 316 infants were included in this study. Of the 316 infants, at least one respiratory tract pathogen was detected in 75% (237/316). Respiratory syncytial virus (RSV) was the most common virus identified in 127 infants (40.1%) followed by rhinovirus (n = 78, 24.6%). In this study, where viral agents were determined via PCR in patients who were followed-up due to the diagnosis of acute bronchiolitis, RSV was detected as the most common agent, as in other studies. In almost half of the RSV-positive patients, RSV was accompanied by a second or third agent.

摘要

本研究的目的是评估因急性细支气管炎住院患者的病毒感染频率、季节性以及临床和人口统计学特征。对316名2岁以下因急性病毒性细支气管炎住院的婴儿进行了一项横断面描述性研究。采用聚合酶链反应(PCR)检测呼吸道感染病原体。本研究共纳入316名婴儿。在这316名婴儿中,75%(237/316)检测到至少一种呼吸道病原体。呼吸道合胞病毒(RSV)是在127名婴儿(40.1%)中鉴定出的最常见病毒,其次是鼻病毒(n = 78,24.6%)。在本研究中,通过PCR确定因急性细支气管炎诊断而接受随访患者的病毒病原体,与其他研究一样,RSV被检测为最常见病原体。在几乎一半的RSV阳性患者中,RSV与第二种或第三种病原体同时存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8b2/5484425/ce9f7b94a1d4/10.1177_2333794X17714378-fig1.jpg

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