Paprott Rebecca, Mensink Gert B M, Schulze Matthias B, Thiele Silke, Mühlenbruch Kristin, Scheidt-Nave Christa, Heidemann Christin
Department of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
German Center for Diabetes Research (DZD), Neuherberg, Germany.
BMJ Open. 2017 Jul 9;7(7):e013058. doi: 10.1136/bmjopen-2016-013058.
Over time, prevalence changes in individual diabetes risk factors have been observed for Germany and other European countries. We aimed to investigate the temporal change of a summary measure of type 2 diabetes risk in Germany.
Comparison of data from two cross-sectional surveys that are about 12 years apart.
Two nationwide health examination surveys representative for the non-institutionalised population aged 18-79 years in Germany.
The study included participants without diagnosed diabetes from the national health examination surveys in 1997-1999 (n=6457) and 2008-2011 (n=6095).
Predicted 5-year type 2 diabetes risk was calculated using the German Diabetes Risk Score (GDRS), which considers information on age, anthropometry, lifestyle factors, hypertension and family history of diabetes.
Between the two survey periods, the overall age- and sex-standardised predicted 5-year risk of type 2 diabetes decreased by 27% from 1.5% (95% CI 1.4% to 1.6%) to 1.1% (1.0% to 1.2%). The decrease in red meat intake and waist circumference had the highest impact on the overall decrease in diabetes risk. In stratified analyses, diabetes risk decreased among both sexes and within strata of age and body mass index. Diabetes risk also decreased among highly educated persons, but remained unchanged among persons with a middle or low educational level.
Monitoring type 2 diabetes risk by a summary measure such as the GDRS could essentially contribute to interpret the dynamics in diabetes epidemiology.
长期以来,德国和其他欧洲国家已观察到个体糖尿病风险因素的患病率变化。我们旨在调查德国2型糖尿病风险综合指标的时间变化情况。
对相隔约12年的两项横断面调查数据进行比较。
两项全国性健康检查调查,代表德国18 - 79岁非机构化人群。
研究纳入了1997 - 1999年(n = 6457)和2008 - 2011年(n = 6095)全国健康检查调查中未被诊断出患有糖尿病的参与者。
使用德国糖尿病风险评分(GDRS)计算预测的5年2型糖尿病风险,该评分考虑了年龄、人体测量学、生活方式因素、高血压和糖尿病家族史等信息。
在两个调查期间,按年龄和性别标准化的总体预测5年2型糖尿病风险从1.5%(95%CI 1.4%至1.6%)下降了27%,降至1.1%(1.0%至1.2%)。红肉摄入量和腰围的下降对糖尿病风险的总体下降影响最大。在分层分析中,男女以及不同年龄和体重指数分层中的糖尿病风险均有所下降。高学历人群的糖尿病风险也有所下降,但中等或低学历人群的糖尿病风险保持不变。
通过诸如GDRS这样的综合指标监测2型糖尿病风险,对于解释糖尿病流行病学动态可能具有重要意义。