Zanaboni Dina Carlotta, Porta Mauro, Saleh Christian, Servello Domenico
Tourette Syndrome Centre, Clinical and Research Galeazzi Hospital, Milan 20161, Italy.
Brain Sci. 2017 Jul 9;7(7):80. doi: 10.3390/brainsci7070080.
(1) Background: Literature suggests that high levels of dopamine are associated with creative thoughts. Tourette Syndrome (TS) patients have high dopamine levels, while Parkinson's Disease (PD) subjects have low dopamine levels. Consequently, TS individuals are supposed to have a major and PD patients less creative output. Moreover, dopamine medications may alter the level of creativity, and therefore Quality of Life, in both pathologies. (2) Methods: The aim of the study was to verify the hypothesis of TS patients having higher creative scores than PD patients. The assessment consisted of the administration of the Creative Thinking ASK Test. There were 54 participants-36 males and 18 females-i.e., 27 TS patients and 27 PD subjects. Age of the sample was 35 to 57 years old, high school certificate was required. (3) Results: TS sample (103.11 ASK average score) was more creative than PD sample (94.11 ASK average score). (4) Conclusions: The results supported the aforementioned hypothesis: TS sample resulted in having higher creative scores than PD sample. Dopamine and other neurotransmitters of TS and PS appear to affect subject's creativity. Further studies with creative assessments in TS and PD patients are needed to support the preliminary results of our study.
(1)背景:文献表明,高水平的多巴胺与创造性思维有关。妥瑞氏症(TS)患者多巴胺水平较高,而帕金森病(PD)患者多巴胺水平较低。因此,预计TS患者的创造力较强,而PD患者的创造力较弱。此外,多巴胺药物可能会改变这两种疾病患者的创造力水平,进而影响其生活质量。(2)方法:本研究旨在验证TS患者的创造性得分高于PD患者这一假设。评估采用了创造性思维ASK测试。共有54名参与者,其中男性36名,女性18名,即27名TS患者和27名PD患者。样本年龄在35至57岁之间,要求具有高中文凭。(3)结果:TS样本(ASK平均得分103.11)比PD样本(ASK平均得分94.11)更具创造力。(4)结论:结果支持了上述假设:TS样本的创造性得分高于PD样本。TS和PD患者体内的多巴胺及其他神经递质似乎会影响其创造力。需要对TS和PD患者进行更多创造性评估研究,以支持本研究的初步结果。