Department of Microbiology, Immunology and Pathology, Arthropod-borne and Infectious Diseases Laboratory, Colorado State University, Fort Collins, CO, United States.
Department of Microbiology, Immunology and Pathology, Arthropod-borne and Infectious Diseases Laboratory, Colorado State University, Fort Collins, CO, United States.
Virus Res. 2018 Aug 2;254:1-9. doi: 10.1016/j.virusres.2017.07.011. Epub 2017 Jul 11.
Zika virus (ZIKV; Genus Flavivirus, Family Flaviviridae) has recently emerged in Asia and the Americas to cause large outbreaks of human disease. The outbreak has been characterized by high attack rates, birth defects in infants and severe neurological complications in adults. ZIKV is transmitted to humans by Aedes mosquitoes, but recent evidence implicates sexual transmission as playing an important role as well. This review highlights the transmission of ZIKV in humans, with a focus on both mosquito and sexually-transmitted routes and their outcomes. We also discuss critical directions for future research.
Zika 病毒（ZIKV；属黄病毒，黄病毒科）最近在亚洲和美洲出现，导致了大规模的人类疾病爆发。此次疫情的特点是发病率高、婴儿出生缺陷和成人严重神经并发症。ZIKV 通过埃及伊蚊传播给人类，但最近的证据表明，性传播也起着重要作用。本综述重点介绍了 ZIKV 在人类中的传播，包括蚊媒和性传播途径及其后果。我们还讨论了未来研究的关键方向。
