Yao Mengyun, Hu Tingting, Wang Yinfeng, Du Yongjiang, Hu Changchang, Wu Ruijin
Department of Gynecology, Women's Hospital, School of Medicine, Zhejiang University, 1Xueshi Road, Hangzhou 310006, P.R. China.
Department of Gynecology, Women's Hospital, School of Medicine, Zhejiang University, 1Xueshi Road, Hangzhou 310006, P.R. China.
Environ Pollut. 2017 Oct;229:837-845. doi: 10.1016/j.envpol.2017.06.088. Epub 2017 Jul 31.
With the progress of global industrialization and environmental deterioration, the relationship between human health and the living environment has become an increasing focus of attention. Polychlorinated biphenyls (PCBs, including dioxin-like polychlorinated biphenyls and non-dioxin-like polychlorinated biphenyls), as part of the organic chlorine contaminants, have been suspected as playing a role in the etiopathogenesis of endometriosis. Several population-based studies have proposed that exposure to PCBs may increase the risk of developing endometriosis, while some epidemiological studies have failed to find any association between PCBs and endometriosis. The purpose of this review is to discuss the potential pathophysiological relationship between endometriosis and PCBs with a focus on both dioxin-like polychlorinated biphenyls and non-dioxin-like polychlorinated biphenyls.
随着全球工业化进程的推进和环境恶化，人类健康与生活环境之间的关系日益受到关注。多氯联苯（PCBs，包括类二噁英多氯联苯和非类二噁英多氯联苯）作为有机氯污染物的一部分，被怀疑在子宫内膜异位症的发病机制中起作用。几项基于人群的研究表明，接触多氯联苯可能会增加患子宫内膜异位症的风险，而一些流行病学研究未能发现多氯联苯与子宫内膜异位症之间存在任何关联。本综述的目的是讨论子宫内膜异位症与多氯联苯之间潜在的病理生理关系，重点关注类二噁英多氯联苯和非类二噁英多氯联苯。
