2013年在意大利、2015年至2016年在西班牙和比利时的沙门氏菌和大肠杆菌中发现的新型质粒介导的黏菌素耐药mcr-4基因
Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016.
作者信息
Carattoli Alessandra, Villa Laura, Feudi Claudia, Curcio Ludovica, Orsini Serenella, Luppi Andrea, Pezzotti Giovanni, Magistrali Chiara Francesca
机构信息
Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
出版信息
Euro Surveill. 2017 Aug 3;22(31). doi: 10.2807/1560-7917.ES.2017.22.31.30589.
A novel mcr colistin resistance gene was identified in a strain of Salmonella enterica, monophasic variant of serovar Typhimurium (4,5,12:i:- ), isolated from a pig at slaughter in Italy in 2013, and in Escherichia coli strains collected during routine diagnostic of post-weaning diarrhoea in pigs from Spain and Belgium in 2015 and 2016. Immediate implementation of mcr-screening including this novel gene variant is required for Salmonella and E. coli from humans and food-producing animals in Europe.
2013年，在意大利一头待屠宰猪身上分离出的鼠伤寒沙门氏菌单相变种（4,5,12:i:-）肠炎沙门氏菌菌株中，以及2015年和2016年在西班牙和比利时猪断奶后腹泻常规诊断期间收集的大肠杆菌菌株中，发现了一种新的mcr黏菌素抗性基因。欧洲对来自人类和食用动物的沙门氏菌和大肠杆菌，需要立即实施包括这种新基因变体在内的mcr筛查。
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