Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA; Program in Occupational Therapy, Washington University, St. Louis, MO, USA.
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Neuroimage. 2017 Nov 1;161:80-93. doi: 10.1016/j.neuroimage.2017.08.025. Epub 2017 Aug 10.
Head motion systematically distorts clinical and research MRI data. Motion artifacts have biased findings from many structural and functional brain MRI studies. An effective way to remove motion artifacts is to exclude MRI data frames affected by head motion. However, such post-hoc frame censoring can lead to data loss rates of 50% or more in our pediatric patient cohorts. Hence, many scanner operators collect additional 'buffer data', an expensive practice that, by itself, does not guarantee sufficient high-quality MRI data for a given participant. Therefore, we developed an easy-to-setup, easy-to-use Framewise Integrated Real-time MRI Monitoring (FIRMM) software suite that provides scanner operators with head motion analytics in real-time, allowing them to scan each subject until the desired amount of low-movement data has been collected. Our analyses show that using FIRMM to identify the ideal scan time for each person can reduce total brain MRI scan times and associated costs by 50% or more.
头部运动会系统性地扭曲临床和研究用磁共振成像(MRI)数据。运动伪影已经使许多结构性和功能性脑 MRI 研究的结果产生偏差。一种有效去除运动伪影的方法是排除受头部运动影响的 MRI 数据帧。然而,这种事后的逐帧剔除可能会导致我们的儿科患者队列数据丢失率达到 50%或更高。因此,许多扫描器操作人员会收集额外的“缓冲数据”,这种昂贵的做法本身并不能保证给定参与者有足够高质量的 MRI 数据。因此,我们开发了一套易于设置和使用的实时框架综合磁共振监测(FIRMM)软件套件,为扫描器操作人员实时提供头部运动分析,使他们能够扫描每个受试者,直到收集到所需数量的低运动数据。我们的分析表明,使用 FIRMM 来确定每个人的理想扫描时间,可以将大脑整体 MRI 扫描时间和相关成本降低 50%或更多。