Kaneko Hiroki, Matsuura Toshiyuki, Takayama Kei, Ito Yasuki, Iwase Takeshi, Ueno Shinji, Nonobe Norie, Yasuda Shunsuke, Kataoka Keiko, Terasaki Hiroko
Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ophthalmologica. 2017;238(4):226-235. doi: 10.1159/000479482. Epub 2017 Aug 31.
The aim of this study was to examine the change in retinal thickness after vitrectomy with internal limiting membrane (ILM) peeling and/or silicone oil (SO) endotamponade in proliferative diabetic retinopathy (PDR).
The actual amount and ratio of changes in the retinal thickness were calculated.
Compared to control eyes in the ILM peeling (-)/SO (-) group, the central, superior inner, and temporal inner retina in the ILM peeling (+)/SO (-) group, the central and superior inner retina in the ILM peeling (-)/SO (+) group, and the central, inferior inner, temporal inner, and nasal inner retina in the ILM peeling (+)/SO (+) group showed a significant reduction of the retinal thickness. The central, superior inner, and temporal inner retina in the ILM peeling (+)/SO (-) group, the central and superior inner retina in the ILM peeling (-)/SO (+) group, and the central, superior inner, inferior inner, and temporal inner retina in the ILM peeling (+)/SO (+) group showed a significantly increased reduction rate of the retinal thickness compared to the control group.
Macular retinal thinning in PDR was observed after ILM peeling and SO endotamponade, and it was increased by the combination of these 2 factors.
本研究的目的是探讨增殖性糖尿病视网膜病变（PDR）患者行玻璃体切割联合内界膜（ILM）剥除和/或硅油（SO）眼内填充术后视网膜厚度的变化。
计算视网膜厚度变化的实际量和变化率。
与ILM剥除（-）/SO（-）组的对照眼相比，ILM剥除（+）/SO（-）组的中央、上内侧和颞内侧视网膜，ILM剥除（-）/SO（+）组的中央和上内侧视网膜，以及ILM剥除（+）/SO（+）组的中央、下内侧、颞内侧和鼻内侧视网膜的厚度均显著降低。与对照组相比，ILM剥除（+）/SO（-）组的中央、上内侧和颞内侧视网膜，ILM剥除（-）/SO（+）组的中央和上内侧视网膜，以及ILM剥除（+）/SO（+）组的中央、上内侧、下内侧和颞内侧视网膜的厚度降低率显著增加。
PDR患者在ILM剥除和SO眼内填充术后出现黄斑视网膜变薄，且这两种因素联合作用会加剧这种变薄。
