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沙特阿拉伯西海岸细颗粒物空气污染与心肺疾病发病率的关联

Association of fine particulate air pollution with cardiopulmonary morbidity in Western Coast of Saudi Arabia.

作者信息

Nayebare Shedrack R, Aburizaiza Omar S, Siddique Azhar, Carpenter David O, Zeb Jahan, Aburizaiza Abdullah J, Pantea Cristian, Hussain Mirza M, Khwaja Haider A

机构信息

Department of Environmental Health Sciences, School of Public Health, University at Albany, Albany, New York, USA. E-mail.

出版信息

Saudi Med J. 2017 Sep;38(9):905-912. doi: 10.15537/smj.2017.9.18545.

Abstract

To assess cardiopulmonary morbidity associated with daily exposures to PM2.5 in Western Coast of Saudi Arabia. Methods: We monitored 24-h PM2.5 and its constituents including black carbon (BC), particulate sulfate (p-SO42-), nitrate (p-NO3-), ammonium (p-NH4+) and trace elements (TEs) at a site in Rabigh, Saudi Arabia from May to June 2013 with simultaneous collection of hospital data (N=2513). Cardiopulmonary morbidity risk was determined in a generalized linear time-series model.  Results: Exposure to PM2.5 was associated with a 7.6% (p=0.056) increase in risk of respiratory disease (RD) in females. Black carbon increased RD morbidity risk by 68.1% (p=0.056) in females. Exposure to p-SO42- increased the cardiovascular disease (CVD) risk by up to 5.3% (p=0.048) in males; and RD by 2.9% (p=0.037) in females and 2.5% (p=0.022) in males. The p-NH4+ increased CVD risk by up to 20.3% (p=0.033) in males; and RD by 10.7% (p=0.014) in females and 8% (p=0.031) in males. No statistically significant association was observed for p-NO3- and TEs exposure. Conclusion: Overall, results show an increased risk for cardiopulmonary morbidity following exposure to air pollution.

摘要

评估沙特阿拉伯西海岸每日接触细颗粒物(PM2.5)所导致的心肺疾病发病率。方法:2013年5月至6月,我们在沙特阿拉伯拉比格的一个地点监测了24小时的PM2.5及其成分,包括黑碳(BC)、颗粒硫酸盐(p-SO42-)、硝酸盐(p-NO3-)、铵(p-NH4+)和微量元素(TEs),同时收集了医院数据(N = 2513)。在广义线性时间序列模型中确定心肺疾病发病风险。结果:女性接触PM2.5与呼吸系统疾病(RD)风险增加7.6%(p = 0.056)相关。黑碳使女性RD发病风险增加68.1%(p = 0.056)。男性接触p-SO42-使心血管疾病(CVD)风险增加高达5.3%(p = 0.048);女性接触p-SO42-使RD风险增加2.9%(p = 0.037),男性增加2.5%(p = 0.022)。p-NH4+使男性CVD风险增加高达20.3%(p = 0.033);女性接触p-NH4+使RD风险增加10.7%(p = 0.014),男性增加8%(p = 0.031)。未观察到接触p-NO3-和TEs有统计学显著关联。结论:总体而言,结果表明接触空气污染后心肺疾病发病风险增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b1f/5654024/d2e1d4a3d7a3/SaudiMedJ-38-905-g004.jpg

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