慢性硬膜下血肿：关于硬膜下膜与痴呆的观点
Chronic Subdural Hematoma: A Perspective on Subdural Membranes and Dementia.
作者信息
Sahyouni Ronald, Goshtasbi Khodayar, Mahmoodi Amin, Tran Diem Kieu, Chen Jefferson W
机构信息
University of California, Irvine, School of Medicine, Irvine, California, USA; Department of Biomedical Engineering, University of California, Irvine, Samueli School of Engineering, Irvine, California, USA.
University of California, Irvine, School of Medicine, Irvine, California, USA.
出版信息
World Neurosurg. 2017 Dec;108:954-958. doi: 10.1016/j.wneu.2017.09.063. Epub 2017 Sep 19.
OBJECTIVE
To review the complex pathogenesis of the subdural membrane and the link between head trauma, dementia, and dural lymphatics.
METHODS
A thorough literature search of published English-language articles was performed using PubMed, Ovid, and Cochrane databases.
RESULTS
Chronic subdural hematoma (cSDH) is a common intracranial pathology and a leading cause of reversible dementia. cSDH is projected to affect at least 60,000 new individuals in the United States annually by 2030. This condition can result from mild to moderate head trauma that leads to hemorrhaging in the dura-arachnoid interface. The short-term and long-term effects of cSDH and the subdural membrane on the pathogenesis of dementia and the newly discovered dural lymphatics is a topic of increasing importance.
CONCLUSIONS
Further research into the possible link between traumatic brain injury and cSDH in particular and dural lymphatics and intracranial fluid dynamics is warranted.
目的
综述硬膜下膜的复杂发病机制以及头部创伤、痴呆和硬脑膜淋巴管之间的联系。
方法
使用PubMed、Ovid和Cochrane数据库对已发表的英文文章进行全面的文献检索。
结果
慢性硬膜下血肿（cSDH）是一种常见的颅内病变，也是可逆性痴呆的主要原因。预计到2030年，美国每年至少有60000名新患者会受到cSDH影响。这种情况可能由轻度至中度头部创伤导致硬脑膜-蛛网膜界面出血引起。cSDH和硬膜下膜对痴呆发病机制以及新发现的硬脑膜淋巴管的短期和长期影响是一个越来越重要的话题。
结论
有必要进一步研究创伤性脑损伤与cSDH之间，特别是与硬脑膜淋巴管和颅内流体动力学之间可能存在的联系。
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