文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

银纳米颗粒对 、 和 的抗真菌效果评估

Evaluation of Antifungal Effect of Silver Nanoparticles Against , and .

作者信息

Ayatollahi Mousavi Seyyed Amin, Salari Samira, Hadizadeh Sanaz

机构信息

Department of Medical Mycology and Parasitology, School of Medicine, Medical University of Kerman, Kerman, Iran.

Research Center for Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

Iran J Biotechnol. 2015 Dec;13(4):38-42. doi: 10.15171/ijb.1302.

DOI:10.15171/ijb.1302
PMID:28959308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5492235/
Abstract

BACKGROUND: Dermatophytosis is the common cutaneous infections in humans and animals, which is caused by the keratinophylic fungus called dermatophytes. In recent years, drugs resistance in pathogenic fungi, including dermatophyte strains to the current antifungals have been increased. OBJECTIVES: The aim of this study was to evaluate the antifungal efficacy of AgNPs against , and . MATERIALS AND METHODS: The antifungal susceptibility of nanosilver particles compared with griseofulvin (GR). Its efficacy was investigated against three strains of dermatophytes by both agar dilution and broth microdilution test (BMD). RESULTS: The average minimum inhibitory concentration (MIC) AgNPs on , and M. gypseum were 200, 180 and 170 μg.mL, respectively. Whereas these strains showed MIC of 25, 100 and 50 μg.mL for GR. CONCLUSIONS: Our finding indicated that the AgNPs was less active than GR but it had anti-dermatophytic effect.

摘要

背景：皮肤癣菌病是人和动物常见的皮肤感染，由称为皮肤癣菌的嗜角质真菌引起。近年来，包括皮肤癣菌菌株在内的致病真菌对当前抗真菌药物的耐药性有所增加。 目的：本研究旨在评估纳米银颗粒对[具体菌株1]、[具体菌株2]和[具体菌株3]的抗真菌效果。 材料与方法：将纳米银颗粒的抗真菌敏感性与灰黄霉素（GR）进行比较。通过琼脂稀释法和肉汤微量稀释法（BMD）研究其对三株皮肤癣菌的疗效。 结果：纳米银颗粒对[具体菌株1]、[具体菌株2]和石膏样小孢子菌的平均最低抑菌浓度（MIC）分别为200、180和170μg/mL。而这些菌株对灰黄霉素的MIC分别为25、100和50μg/mL。 结论：我们的研究结果表明，纳米银颗粒的活性低于灰黄霉素，但具有抗皮肤癣菌的作用。

相似文献

[1]
Evaluation of Antifungal Effect of Silver Nanoparticles Against , and .

Iran J Biotechnol. 2015-12

[2]
In vitro antifungal activity of heterocyclic organoboron compounds against Trichophyton mentagrophytes and Microsporum canis obtained from clinical isolates.

Braz J Microbiol. 2022-9

[3]
Antifungal activity of methanol extract against , , and on rat dermatophytosis models.

Curr Med Mycol. 2023-3

[4]
Susceptibility of clinically important dermatophytes against statins and different statin-antifungal combinations.

Med Mycol. 2014-2

[5]
In vitro susceptibility of dermatomycoses agents to six antifungal drugs and evaluation by fractional inhibitory concentration index of combined effects of amorolfine and itraconazole in dermatophytes.

Microbiol Immunol. 2014-1

[6]
Detection of dermatophytes in healthy companion dogs and cats in eastern India.

Iran J Vet Res. 2016

[7]
Molecular Identification and Antifungal Susceptibility Patterns of Dermatophytes Isolated from Companion Animals with Clinical Symptoms of Dermatophytosis.

J Vet Res. 2021-4-23

[8]
Inibitory effects of linalool on fungal pathogenicity of clinical isolates of Microsporum canis and Microsporum gypseum.

Mycoses. 2017-6

[9]
Comparison of in vitro activity of five antifungal agents against dermatophytes, using the agar dilution and broth microdilution methods.

Rev Soc Bras Med Trop. 2009

[10]
Evaluation of antifungal activities of the essential oil and various extracts of Nigella sativa and its main component, thymoquinone against pathogenic dermatophyte strains.

J Mycol Med. 2014-12

引用本文的文献

[1]
Nail Lacquer Containing and Essential Oils and Biogenic Silver Nanoparticles for Onychomycosis: Development, Characterization, and Evaluation of Antifungal Efficacy.

Antibiotics (Basel). 2024-9-17

[2]
Potential Treatment of Dermatophyte in Rat Model Using Topical Green Biosynthesized Silver Nanoparticles with Extract.

Molecules. 2023-2-5

[3]
A Promising Antifungal and Antiamoebic Effect of Silver Nanorings, a Novel Type of AgNP.

Antibiotics (Basel). 2022-8-3

[4]
In vitro antifungal activity of heterocyclic organoboron compounds against Trichophyton mentagrophytes and Microsporum canis obtained from clinical isolates.

Braz J Microbiol. 2022-9

[5]
First Report of the Biosynthesis and Characterization of Silver Nanoparticles Using subsp. Fruit Extracts and Their Antioxidant, Antimicrobial and Cytotoxic Properties.

Nanomaterials (Basel). 2022-5-7

[6]
The Efficacy of Green Synthesized Nanosilver in Reducing the Incidence of Post-Harvest Apple Fruit Brown Rot.

J Fungi (Basel). 2021-6-10

[7]
Antibacterial Activity of Silver and Its Application in Dentistry, Cardiology and Dermatology.

Microorganisms. 2020-9-11

[8]
Proximal subungual onychomycosis of due to .

Pan Afr Med J. 2020-3-19

[9]
Glutamic acid assisted phyto-management of silver-contaminated soils through sunflower; physiological and biochemical response.

Environ Sci Pollut Res Int. 2018-6-27

[10]
Plant-mediated green synthesis of silver nanoparticles using Trifolium resupinatum seed exudate and their antifungal efficacy on Neofusicoccum parvum and Rhizoctonia solani.

IET Nanobiotechnol. 2016-8

本文引用的文献

[1]
Yeasts as important agents of onychomycosis: in vitro activity of propolis against yeasts isolated from patients with nail infection.

J Altern Complement Med. 2012-9-6

[2]
Dermatophytes from skin lesions of domestic animals in Nsukka, Enugu State, Nigeria.

Vet Dermatol. 2012-12

[3]
Silver nanoparticles as potential antiviral agents.

Molecules. 2011-10-24

[4]
Nanosilver--the burgeoning therapeutic molecule and its green synthesis.

Biotechnol Adv. 2009-8-15

[5]
Comparison of in vitro activity of five antifungal agents against dermatophytes, using the agar dilution and broth microdilution methods.

Rev Soc Bras Med Trop. 2009

[6]
Fungus-mediated synthesis of silver nanoparticles and their activity against pathogenic fungi in combination with fluconazole.

Nanomedicine. 2009-7-16

[7]
Rapid detection of dermatophytes from skin and hair.

BMC Res Notes. 2009-4-18

[8]
Silver nanoparticles as a new generation of antimicrobials.

Biotechnol Adv. 2009

[9]
Antifungal effect of silver nanoparticles on dermatophytes.

J Microbiol Biotechnol. 2008-8

[10]
In vitro antifungal drug susceptibilities of dermatophytes microconidia and arthroconidia.

J Antimicrob Chemother. 2008-10

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索