吡唑衍生物的合成和生物属性：综述。
The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review.
机构信息
Department of Chemistry, Banasthali University, Banasthali Bansthali-304022, India.
Department of Pharmacy, Banasthali University, Banasthali, Banasthali-304022, India.
出版信息
Mini Rev Med Chem. 2018;18(11):918-947. doi: 10.2174/1389557517666170927160919.
Abstract
Pyrazole nucleus is a unique structural scaffold which acts as an interesting template for combinatorial as well as medicinal chemistry. This review presents a detailed overview on the synthesis, QSAR and pharmacological applications of pyrazole. In addition, it covers most recent reports on structural modifications on pyrazole illustrating vital structural activity relationship.
摘要
吡唑核是一种独特的结构支架，可用作组合化学和药物化学的有趣模板。本文综述了吡唑的合成、QSAR 和药理学应用的详细概述。此外，它还涵盖了最近关于吡唑结构修饰的报告，说明了重要的结构活性关系。
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