Department of Chemistry, Banasthali University, Banasthali Bansthali-304022, India.
Department of Pharmacy, Banasthali University, Banasthali, Banasthali-304022, India.
Mini Rev Med Chem. 2018;18(11):918-947. doi: 10.2174/1389557517666170927160919.
Pyrazole nucleus is a unique structural scaffold which acts as an interesting template for combinatorial as well as medicinal chemistry. This review presents a detailed overview on the synthesis, QSAR and pharmacological applications of pyrazole. In addition, it covers most recent reports on structural modifications on pyrazole illustrating vital structural activity relationship.
吡唑核是一种独特的结构支架，可用作组合化学和药物化学的有趣模板。本文综述了吡唑的合成、QSAR 和药理学应用的详细概述。此外，它还涵盖了最近关于吡唑结构修饰的报告，说明了重要的结构活性关系。
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