通过匿名DNA探针检测到的限制性片段长度多态性定位于人类16号染色体的特定区间。
Restriction fragment length polymorphisms detected by anonymous DNA probes mapped to defined intervals of human chromosome 16.
作者信息
Hyland V J, Grist S, Sutherland G R
机构信息
Department of Histopathology, Adelaide Children's Hospital, North Adelaide, Australia.
出版信息
Hum Genet. 1988 Jul;79(3):277-9. doi: 10.1007/BF00366251.
Three anonymous DNA probes ACH207, ACH224, and ACH202, isolated from a flow-purified chromosome 16 library and mapped to defined intervals of human chromosome 16, detected restriction fragment length polymorphisms (RFLPs). The RFLPs were of simple two allele types. The ACH207 (D16S4) probe detected a TaqI and an MspI RFLP with polymorphism information content (PIC) values of 0.30 and 0.27; the ACH224 (D16S5) probe detected an RsaI RFLP, PIC value of 0.34; and the ACH202 (D16S4) probe detected an XbaI RFLP, PIC value of 0.22.
从流式纯化的16号染色体文库中分离出的三个匿名DNA探针ACH207、ACH224和ACH202，定位到人类16号染色体的特定区间，检测到限制性片段长度多态性（RFLP）。这些RFLP为简单的双等位基因类型。ACH207（D16S4）探针检测到一个TaqI和一个MspI RFLP，多态性信息含量（PIC）值分别为0.30和0.27；ACH224（D16S5）探针检测到一个RsaI RFLP，PIC值为0.34；ACH202（D16S4）探针检测到一个XbaI RFLP，PIC值为0.22。
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