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老年人步行速度、危险因素与心血管事件——系统评价

Walking Speed, Risk Factors, and Cardiovascular Events in Older Adults-Systematic Review.

作者信息

Fonseca Alves David J, Bartholomeu-Neto João, Júnior Edis Rodrigues, Ribeiro Zarricueta Bárbara S, Nóbrega Otávio T, Córdova Claudio

机构信息

1Physical Education Program, Catholic University of Brasília (UCB-DF), Brasília, Brazil; 2Medical Faculty, University of Brasília (UnB), Brasília, Brazil; and 3Gerontology Program, Catholic University of Brasília (UCB-DF), Brasília, Brazil.

出版信息

J Strength Cond Res. 2017 Nov;31(11):3235-3244. doi: 10.1519/JSC.0000000000002182.

DOI:10.1519/JSC.0000000000002182
PMID:29065080
Abstract

Fonseca Alves, DJ, Bartholomeu-Neto, J, Júnior, ER, Ribeiro Zarricueta, BS, Nóbrega, OT, and Córdova, C. Walking speed, risk factors, and cardiovascular events in older adults-systematic review. J Strength Cond Res 31(11): 3235-3244, 2017-It is important that new clinical measures can identify risk factors and predict cardiovascular events. Although the walking speed (WS) test is a potential candidate, consolidating data from multiple studies is required to determine comparative references. We examined the associations of WS measures with markers of cardiovascular risk and with cardiovascular events in noninstitutionalized subjects older than 60 years. A systematic review of observational studies was conducted using MEDLINE and SCOPUS from inception of the databases to December 2014, aiming at studies that evaluated WS as the primary outcome (usual or maximal pace) within a distance ≤20 m associated with cardiovascular health. All 15 included studies (29,845 subjects) reported significant associations of WS with different cardiovascular risk factors (coronary artery calcification, C-reactive protein, hypertension, diabetes, and intima-media thickness) and occurrence of cardiovascular events (peripheral artery disease, stroke, and mortality). Approximately 80% of the studies used a distance ≤6 m and WS at usual pace. There was high heterogeneity in the risk thresholds established by different studies. Our results suggest usefulness of the WS test as a tool for cardiovascular risk stratification in older adults. However, the variation in speed thresholds and diversity of protocols among studies suggest caution when generalizing results to different older adult populations. Because the WS test is a simple, cheap, and safe tool to administer, we make suggestions for its standardization in future studies.

摘要

丰塞卡·阿尔维斯、DJ、巴塞洛缪 - 内托、J、朱尼尔、ER、里贝罗·扎里库埃塔、BS、诺布雷加、OT和科尔多瓦、C。老年人步行速度、危险因素与心血管事件——系统评价。《力量与体能研究杂志》31(11): 3235 - 3244,2017年——重要的是,新的临床测量方法能够识别危险因素并预测心血管事件。尽管步行速度(WS)测试是一个潜在的候选方法,但需要整合多项研究的数据来确定比较参考标准。我们研究了60岁以上非机构化受试者中WS测量值与心血管风险标志物以及心血管事件之间的关联。使用MEDLINE和SCOPUS对观察性研究进行了系统评价,从数据库创建之初到2014年12月,旨在寻找评估WS作为与心血管健康相关的≤20米距离内的主要结局(通常或最大步速)的研究。所有纳入的15项研究(29845名受试者)均报告了WS与不同心血管危险因素(冠状动脉钙化、C反应蛋白、高血压、糖尿病和内膜中层厚度)以及心血管事件(外周动脉疾病、中风和死亡率)之间存在显著关联。大约80%的研究使用的距离≤6米且为通常步速的WS。不同研究确定的风险阈值存在高度异质性。我们的结果表明WS测试作为老年人心血管风险分层工具的有用性。然而,研究之间速度阈值的差异和方案的多样性表明,在将结果推广到不同老年人群体时要谨慎。由于WS测试是一种简单、廉价且安全的测试工具,我们对其在未来研究中的标准化提出了建议。

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