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对科威特海洋环境中分离的大肠杆菌中抗菌药物耐药性的基线筛查。

Baseline screening for the presence of antimicrobial resistance in E. coli isolated from Kuwait's marine environment.

机构信息

School of Biological Sciences, Plymouth University, Drake Circus, Plymouth, PL4 8AA, UK; Centre for Environment, Fisheries and Aquaculture Science (Cefas), Weymouth laboratory, Barrack Road, Weymouth, Dorset DT4 8UB, UK; Department of Earth & Environmental Sciences, Kuwait University, Faculty of Science, P.O. Box 5969, Safat 13060, Kuwait.

School of Biological Sciences, Plymouth University, Drake Circus, Plymouth, PL4 8AA, UK.

出版信息

Mar Pollut Bull. 2018 Apr;129(2):893-898. doi: 10.1016/j.marpolbul.2017.10.044. Epub 2017 Oct 24.

Abstract

Here we present the findings of a study where 598 isolates of Escherichia coli (351 derived from seawater; 247 derived from the Venus clam, Circenita callipyga) were obtained from Kuwait's marine environment. Isolates were screened for their potential resistance to an array of 23 commonly deployed frontline antibiotics. Results demonstrate the resistant was widespread across all sites with high-levels of resistance (seawater: summer 89-64%; winter 90-57% and biota: summer 77%; winter 88%) observed to at least 1 of the 23 antibiotics tested. Resistance to Ampicillin was by far the most widely observed profile in seawater and biota across both summer and winter seasons, with 55.9 to 70.9% isolates displaying resistance to this antibiotic. This study demonstrates the potential of AMR screening to be used in Kuwait to detect issues related to water quality and the consequences it may pose for human health.

摘要

我们在此介绍一项研究的结果,该研究从科威特的海洋环境中获得了 598 株大肠杆菌(351 株来自海水,247 株来自维纳斯蛤 Circenita callipyga)。对这些分离株进行了一系列 23 种常用一线抗生素的潜在耐药性筛选。结果表明,所有地点的耐药性都很普遍,对 23 种测试抗生素中的至少 1 种表现出高水平耐药性(海水:夏季 89-64%;冬季 90-57%和生物群:夏季 77%;冬季 88%)。在海水和生物群中,夏季和冬季均观察到对氨苄西林的耐药性最为广泛,55.9%至 70.9%的分离株对该抗生素表现出耐药性。本研究表明,在科威特,AMR 筛选有可能用于检测与水质相关的问题及其可能对人类健康造成的后果。

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