Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Biomed Pharmacother. 2018 Jan;97:91-97. doi: 10.1016/j.biopha.2017.10.119. Epub 2017 Nov 6.
Endometriosis, an estrogen-dependent inflammatory disease, is one of the most common chronic gynecological disorders affecting women in reproductive age. It is characterized by the presence of endometrial-like tissue outside the uterus. The exact pathophysiology of endometriosis is not still well-known, but the immune system and inflammation have been considered as pivotal factors in disease progression. Turmeric, an important spice all around the world, is obtained from the rhizomes of Curcuma longa, a member of the Zingiberaceae family. It has been used in the prevention and treatment of many diseases since ancient times. Curcumin is the principal polyphenol isolated from turmeric. Several evidences have shown the anti-inflammatory, antioxidant, anti-tumor, anti-angiogenesis, and anti-metastatic activities of curcumin. In this review, relevant articles on the effect of curcumin on endometriosis and possible molecular mechanisms are discussed.
子宫内膜异位症是一种雌激素依赖性炎症性疾病，是影响生育期妇女的最常见慢性妇科疾病之一。其特征是在子宫外存在类似子宫内膜的组织。子宫内膜异位症的确切病理生理学尚不清楚，但免疫系统和炎症已被认为是疾病进展的关键因素。姜黄，一种在世界各地都很重要的香料，是从姜科姜黄属的根茎中获得的。自古以来，它就被用于预防和治疗许多疾病。姜黄素是从姜黄中分离出来的主要多酚。有几项证据表明姜黄素具有抗炎、抗氧化、抗肿瘤、抗血管生成和抗转移活性。在这篇综述中，讨论了姜黄素对子宫内膜异位症的影响及其可能的分子机制的相关文章。
