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Evaluation of sperm chromatin structure and DNA strand breaks is an important part of clinical male fertility assessment.

作者信息

Evenson Donald P

机构信息

South Dakota State University, Brookings, SD, USA.

Department of OB/GY, Sanford Medical School, University of South Dakota, Sioux Falls, SD, USA.

出版信息

Transl Androl Urol. 2017 Sep;6(Suppl 4):S495-S500. doi: 10.21037/tau.2017.07.20.

DOI:10.21037/tau.2017.07.20
PMID:29082168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5643675/
Abstract
摘要

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Evaluation of sperm DNA structure, fragmentation and decondensation: an essential tool in the assessment of male infertility.精子DNA结构、片段化及解聚的评估:男性不育评估中的一项重要工具。
Transl Androl Urol. 2017 Sep;6(Suppl 4):S553-S556. doi: 10.21037/tau.2017.03.11.
2
Association between the MTHFR-C677T isoform and structure of sperm DNA.亚甲基四氢叶酸还原酶 C677T 基因型与精子 DNA 结构的关系。
J Assist Reprod Genet. 2017 Oct;34(10):1283-1288. doi: 10.1007/s10815-017-1015-2. Epub 2017 Aug 25.
3
Inter- and intra-laboratory standardization of TUNEL assay for assessment of sperm DNA fragmentation.
除了基于世界卫生组织(WHO)标准的精液检查外,进行精子 DNA 碎片测试可以更准确地诊断试管婴儿的结果。
BMC Urol. 2023 Apr 29;23(1):78. doi: 10.1186/s12894-023-01257-y.
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Does Choosing Microfluidics for Sperm Sorting Offer an Advantage to Improve Clinical Pregnancies in Donor Egg Recipients?选择微流控技术进行精子分选是否有助于提高供卵受者的临床妊娠率?
J Hum Reprod Sci. 2022 Apr-Jun;15(2):143-149. doi: 10.4103/jhrs.jhrs_15_22. Epub 2022 Jun 30.
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Chronic Prostatitis/Chronic Pelvic Pain Syndrome Leads to Impaired Semen Parameters, Increased Sperm DNA Fragmentation and Unfavorable Changes of Sperm Protamine mRNA Ratio.慢性前列腺炎/慢性骨盆疼痛综合征导致精液参数受损、精子 DNA 碎片化增加和精子鱼精蛋白 mRNA 比例的不利变化。
Int J Mol Sci. 2021 Jul 23;22(15):7854. doi: 10.3390/ijms22157854.
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The Negative Impact of Varicocele on Basic Semen Parameters, Sperm Nuclear DNA Dispersion and Oxidation-Reduction Potential in Semen.精索静脉曲张对精液基本参数、精子核DNA分散度及精液氧化还原电位的负面影响。
Int J Environ Res Public Health. 2021 Jun 2;18(11):5977. doi: 10.3390/ijerph18115977.
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Microbiological Evaluation and Sperm DNA Fragmentation in Semen Samples of Patients Undergoing Fertility Investigation.生育力检查患者精液样本的微生物评估与精子 DNA 碎片化。
Genes (Basel). 2021 Apr 27;12(5):654. doi: 10.3390/genes12050654.
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Sperm chromatin structure assay versus sperm chromatin dispersion kits: Technical repeatability and choice of assisted reproductive technology procedure.精子染色质结构分析与精子染色质扩散试剂盒:技术重复性及辅助生殖技术程序的选择
Clin Exp Reprod Med. 2020 Dec;47(4):277-283. doi: 10.5653/cerm.2020.03860. Epub 2020 Nov 20.
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Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations.精子 DNA 碎片化检测:总结证据和临床实践建议。
Andrologia. 2021 Mar;53(2):e13874. doi: 10.1111/and.13874. Epub 2020 Oct 27.
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Relationship between sperm morphology and sperm DNA dispersion.精子形态与精子DNA分散度之间的关系。
Transl Androl Urol. 2020 Apr;9(2):405-415. doi: 10.21037/tau.2020.01.31.
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Andrology. 2017 May;5(3):477-485. doi: 10.1111/andr.12334. Epub 2017 Feb 28.
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Sperm DNA damage and its role in IVF and ICSI.精子DNA损伤及其在体外受精和卵胞浆内单精子注射中的作用。
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