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血清 Meteorin 样蛋白水平在新诊断为 2 型糖尿病的患者中降低。

Serum Meteorin-like protein levels decreased in patients newly diagnosed with type 2 diabetes.

机构信息

Department of Internal Medicine, Chungnam National University School of Medicine, 266 Munwha-ro, Jung-gu, Daejeon 35015, Republic of Korea.

Department of Medical Science, Chungnam National University School of Medicine, 266 Munwha-ro, Jung-gu, Daejeon 35015, Republic of Korea.

出版信息

Diabetes Res Clin Pract. 2018 Jan;135:7-10. doi: 10.1016/j.diabres.2017.10.005. Epub 2017 Oct 31.

DOI:10.1016/j.diabres.2017.10.005
PMID:29097285
Abstract

We analyzed circulating Meteorin-like (METRNL) levels in human. Serum METRNL levels were significantly lower in subjects with diabetes mellitus compared with those without diabetes. Serum METRNL was negatively correlated with the serum glucose level and insulin resistance. Metformin treatment did not increase the serum METRL levels after 12 weeks.

摘要

我们分析了人类循环中的 Meteorin 样蛋白 (METRNL) 水平。与无糖尿病患者相比，糖尿病患者的血清 METRNL 水平显著降低。血清 METRNL 与血糖水平和胰岛素抵抗呈负相关。二甲双胍治疗 12 周后并未增加血清 METRL 水平。

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