幽门弯曲菌临床分离株对11种抗菌药物的敏感性
Susceptibility of clinical isolates of Campylobacter pyloridis to 11 antimicrobial agents.
作者信息
McNulty C A, Dent J, Wise R
出版信息
Antimicrob Agents Chemother. 1985 Dec;28(6):837-8. doi: 10.1128/AAC.28.6.837.
Abstract
The activities of 11 antimicrobial agents, including two bismuth salts, against 70 strains of Campylobacter pyloridis isolated from gastric biopsy specimens were tested. The isolates were very susceptible to penicillin (the MIC for 90% of the strains tested [MIC90] was 0.03 microgram/ml), erythromycin, cefoxitin (MIC90, 0.12 microgram/ml), gentamicin, and ciprofloxacin (MIC90, 0.25 microgram/ml). The bismuth salts and nalidixic acid had moderate activity (MIC90, 16 to 64 micrograms/ml). Twenty percent of the isolates were resistant to metronidazole (MIC, greater than 1 micrograms/ml), and all were resistant to sulfamethoxazole and trimethoprim (MIC90, greater than 256 micrograms/ml).
摘要
对从胃活检标本中分离出的70株幽门弯曲菌，测试了包括两种铋盐在内的11种抗菌剂的活性。这些分离株对青霉素（90%测试菌株的最低抑菌浓度[MIC90]为0.03微克/毫升）、红霉素、头孢西丁（MIC90，0.12微克/毫升）、庆大霉素和环丙沙星（MIC90，0.25微克/毫升）非常敏感。铋盐和萘啶酸具有中等活性（MIC90，16至64微克/毫升）。20%的分离株对甲硝唑耐药（MIC，大于1微克/毫升），所有分离株均对磺胺甲恶唑和甲氧苄啶耐药（MIC90，大于256微克/毫升）。
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