溢油化学品暴露与深水地平线灾难应急人员的肺功能
Exposure to Oil Spill Chemicals and Lung Function in Deepwater Horizon Disaster Response Workers.
机构信息
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina (Ms Gam, Drs Kwok, Engel, Sandler); Department of Global Environmental Health Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana (Ms Gam, Dr Lichtveld); Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina (Dr Engel); Social & Scientific Systems Inc., Durham, North Carolina (Mr Curry, Mr McGrath, Mr Jackson II); Stewart Exposure Assessments, LLC, Arlington, Virginia (Dr Stewart); Exposure Assessment Applications, LLC, Arlington, Virginia (Mr Stenzel); Pulmonary Division, University of Utah and Intermountain Medical Center, Salt Lake City, Utah (Dr Jensen); Office of the Director, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland (Dr Miller).
出版信息
J Occup Environ Med. 2018 Jun;60(6):e312-e318. doi: 10.1097/JOM.0000000000001292.
OBJECTIVE
The aim of this study was to assess the relationship between total hydrocarbon (THC) exposures attributed to oil spill clean-up work and lung function 1 to 3 years after the Deepwater Horizon (DWH) disaster.
METHODS
We used data from the GuLF STUDY, a large cohort of adults who worked on response to the DWH disaster and others who were safety trained but did not work. We analyzed data from 6288 workers with two acceptable spirometry tests. We estimated THC exposure levels with a job exposure matrix. We evaluated lung function using the forced expiratory volume in 1 second (FEV1; mL), the forced vital capacity (FVC; mL), and the FEV1/FVC ratio (%).
RESULTS
Lung function measures did not differ by THC exposure levels among clean-up workers.
CONCLUSION
We did not observe an association between THC exposure and lung function among clean-up workers 1 to 3 years following the DWH disaster.
目的
本研究旨在评估与深海地平线（DWH）灾难清理工作相关的总碳氢化合物（THC）暴露与肺功能之间的关系，这些暴露发生在灾难发生后 1 至 3 年。
方法
我们使用了 GuLF 研究的数据，该研究是一项针对参与 DWH 灾难应对工作的成年人和其他接受安全培训但未工作的成年人的大型队列研究。我们分析了来自 6288 名具有两份可接受的肺活量测试结果的工人的数据。我们使用职业暴露矩阵评估 THC 暴露水平。我们使用 1 秒用力呼气量（FEV1；mL）、用力肺活量（FVC；mL）和 FEV1/FVC 比值（%）来评估肺功能。
结果
在清理工人中，肺功能指标与 THC 暴露水平之间没有差异。
结论
在 DWH 灾难发生后 1 至 3 年，我们没有观察到清理工人的 THC 暴露与肺功能之间存在关联。
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