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Risk of solid cancer in low dose-rate radiation epidemiological studies and the dose-rate effectiveness factor.低剂量率辐射流行病学研究中实体癌的风险与剂量率有效性因子
Int J Radiat Biol. 2017 Oct;93(10):1064-1078. doi: 10.1080/09553002.2017.1319090. Epub 2017 May 15.
2
Biologically-based mechanistic models of radiation-related carcinogenesis applied to epidemiological data.应用于流行病学数据的基于生物学的辐射相关致癌作用机制模型。
Int J Radiat Biol. 2017 Oct;93(10):1093-1117. doi: 10.1080/09553002.2017.1310405. Epub 2017 Apr 25.
3
Solid Cancer Incidence among the Life Span Study of Atomic Bomb Survivors: 1958-2009.原子弹爆炸幸存者寿命研究中的实体癌发病率：1958 - 2009年
Radiat Res. 2017 May;187(5):513-537. doi: 10.1667/RR14492.1. Epub 2017 Mar 20.
4
DS02R1: Improvements to Atomic Bomb Survivors' Input Data and Implementation of Dosimetry System 2002 (DS02) and Resulting Changes in Estimated Doses.DS02R1：原子弹幸存者输入数据的改进、2002年剂量测定系统（DS02）的实施以及估计剂量的相应变化
Health Phys. 2017 Jan;112(1):56-97. doi: 10.1097/HP.0000000000000598.
5
No evidence for an increase in circulatory disease mortality in astronauts following space radiation exposures.没有证据表明宇航员在接受太空辐射暴露后循环系统疾病死亡率增加。
Life Sci Space Res (Amst). 2016 Aug;10:53-6. doi: 10.1016/j.lssr.2016.08.002. Epub 2016 Aug 20.
6
The role of dose rate in radiation cancer risk: evaluating the effect of dose rate at the molecular, cellular and tissue levels using key events in critical pathways following exposure to low LET radiation.剂量率在辐射致癌风险中的作用：利用低线性能量传递辐射照射后关键途径中的关键事件，在分子、细胞和组织水平评估剂量率的影响。
Int J Radiat Biol. 2016 Aug;92(8):405-26. doi: 10.1080/09553002.2016.1186301. Epub 2016 Jun 7.
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Dose-rate effects in radiation biology and radiation protection.辐射生物学与辐射防护中的剂量率效应。
Ann ICRP. 2016 Jun;45(1_suppl):262-279. doi: 10.1177/0146645316629336.
8
The Increase in Animal Mortality Risk following Exposure to Sparsely Ionizing Radiation Is Not Linear Quadratic with Dose.接触低水平电离辐射后动物死亡率风险的增加与剂量不成线性二次关系。
PLoS One. 2015 Dec 9;10(12):e0140989. doi: 10.1371/journal.pone.0140989. eCollection 2015.
9
Workshop Report on Atomic Bomb Dosimetry--Review of Dose Related Factors for the Evaluation of Exposures to Residual Radiation at Hiroshima and Nagasaki.原子弹剂量测定研讨会报告——广岛和长崎残余辐射暴露评估中与剂量相关因素的综述
Health Phys. 2015 Dec;109(6):582-600. doi: 10.1097/HP.0000000000000395.
10
Risk of cancer from occupational exposure to ionising radiation: retrospective cohort study of workers in France, the United Kingdom, and the United States (INWORKS).职业性接触电离辐射导致癌症的风险：法国、英国和美国工人的回顾性队列研究（INWORKS）
BMJ. 2015 Oct 20;351:h5359. doi: 10.1136/bmj.h5359.

与低剂量和低剂量率辐射风险推断相关研究中的典型剂量和剂量率。

Typical doses and dose rates in studies pertinent to radiation risk inference at low doses and low dose rates.

作者信息

Rühm Werner, Azizova Tamara, Bouffler Simon, Cullings Harry M, Grosche Bernd, Little Mark P, Shore Roy S, Walsh Linda, Woloschak Gayle E

机构信息

Institute of Radiation Protection, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

Southern Urals Biophysics Institute (SUBI), Ozyorskoe Shosse 19, 456780, Ozyorsk, Chelyabinsk Region, Russian Federation.

出版信息

J Radiat Res. 2018 Apr 1;59(suppl_2):ii1-ii10. doi: 10.1093/jrr/rrx093.

DOI:10.1093/jrr/rrx093
PMID:29432579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5941142/
Abstract

In order to quantify radiation risks at exposure scenarios relevant for radiation protection, often extrapolation of data obtained at high doses and high dose rates down to low doses and low dose rates is needed. Task Group TG91 on 'Radiation Risk Inference at Low-dose and Low-dose Rate Exposure for Radiological Protection Purposes' of the International Commission on Radiological Protection is currently reviewing the relevant cellular, animal and human studies that could be used for that purpose. This paper provides an overview of dose rates and doses typically used or present in those studies, and compares them with doses and dose rates typical of those received by the A-bomb survivors in Japan.

摘要

为了量化与辐射防护相关的照射情景下的辐射风险，通常需要将高剂量和高剂量率下获得的数据外推至低剂量和低剂量率。国际放射防护委员会关于“用于放射防护目的的低剂量和低剂量率照射下的辐射风险推断”的第TG91任务组目前正在审查可用于此目的的相关细胞、动物和人体研究。本文概述了这些研究中通常使用或存在的剂量率和剂量，并将它们与日本原子弹幸存者所接受的典型剂量和剂量率进行比较。