Kim Min-Ju, Yim Gyeyoon, Park Hyun-Young
Division of Cardiovascular Diseases, Center for Biomedical Science, National Research Institute of Health, Chungbuk, Korea.
PLoS One. 2018 Feb 20;13(2):e0192934. doi: 10.1371/journal.pone.0192934. eCollection 2018.
Sleep disturbance is one of the common complaints in menopause. This study investigated the relationship between menopausal symptoms and sleep quality in middle-aged women.
This cross-sectional observational study involved 634 women aged 44-56 years attending a healthcare center at Kangbuk Samsung Hospitals. Sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI).Multiple linear regression analysis was performed to assess the associations between Menopause-specific Quality of Life (MENQOL) scores and PSQI scores and Menopause-specific Quality of Life (MENQOL)scores.
The mean PSQI score was 3.6±2.3, and the rates of poor sleep quality(PSQI score > 5) in premenopausal, perimenopausal, and postmenopausal women were 14.4%, 18.2%, and 30.2%, respectively. Total PSQI score, specifically the sleep latency, habitual sleep efficiency and sleep disturbances scores, were significantly increased in postmenopausal women. Multiple linear regression analysis adjusted for age, BMI, hypertension, diabetes, smoking, marital status, family income, education, employment status, parity, physical activity, depression symptoms, perceived stress and menopausal status showed that higher PSQI score was positively correlated with higher vasomotor(ß = 0.240, P = 0.020)and physical(ß = 0.572, P<0.001) scores.
Vasomotor and physical menopause symptoms was related to poor sleep quality. Effective management strategies aimed at reducing menopausal symptoms may improve sleep quality among women around the time of menopause.
睡眠障碍是更年期常见的主诉之一。本研究调查了中年女性更年期症状与睡眠质量之间的关系。
这项横断面观察性研究纳入了634名年龄在44 - 56岁之间、前往江北三星医院医疗中心就诊的女性。使用匹兹堡睡眠质量指数（PSQI）测量睡眠质量。进行多元线性回归分析，以评估更年期特异性生活质量（MENQOL）评分与PSQI评分之间的关联以及更年期特异性生活质量（MENQOL）评分。
PSQI平均得分为3.6±2.3，绝经前、围绝经期和绝经后女性睡眠质量差（PSQI评分>5）的比例分别为14.4%、18.2%和30.2%。绝经后女性的PSQI总分，特别是入睡潜伏期、习惯性睡眠效率和睡眠障碍评分显著升高。在对年龄、体重指数、高血压、糖尿病、吸烟、婚姻状况、家庭收入、教育程度、就业状况、产次、身体活动、抑郁症状、感知压力和绝经状态进行调整的多元线性回归分析中，较高的PSQI评分与较高的血管舒缩（β = 0.240，P = 0.020）和生理（β = 0.572，P<0.001）评分呈正相关。
血管舒缩和生理更年期症状与睡眠质量差有关。旨在减轻更年期症状的有效管理策略可能会改善更年期前后女性的睡眠质量。
