Badulak Jenelle H, Schurr Michael, Sauaia Angela, Ivashchenko Anna, Peltz Erik
University of Washington, Division of Pulmonary, Critical Care and Sleep Medicine, 1959 NE Pacific Street, Seattle, WA 98195, United States.
Mountain Area Health Education Center, Division of General Surgery, 121 Hendersonville Road, Asheville, NC 28803, United States.
Burns. 2018 May;44(3):531-538. doi: 10.1016/j.burns.2018.02.016. Epub 2018 Mar 13.
Recent studies demonstrate that burn patients are undergoing unnecessary intubations. We sought to determine the clinical criteria that predict intubations with benefit.
This was a retrospective review of intubated adults admitted to our center with thermal burns 2008-2013. Criteria for intubation were defined as traditional criteria (suspected smoke inhalation, oropharynx soot, hoarseness, dysphagia, singed facial hair, oral edema, oral burn, non-full thickness facial burns), or ABA criteria as defined by the 2011 ABA guidelines (full thickness facial burns, stridor, respiratory distress, swelling on laryngoscopy, upper airway trauma, altered mentation, hypoxia/hypercarbia, hemodynamic instability). Patients with <26days free from mechanical ventilation (ventilator-free days (VFD)) out of 28, were deemed indicated long-term intubations. Those with ≥26 VFD were deemed unnecessary short-term intubations.
Of 218 patients, 151 had long-term and 67 had short-term intubations. Long-term intubation was strongly associated with ABA criteria (77.5%) compared to traditional criteria (22.5%) (p<0.001). Sensitivity of ABA criteria for long-term intubation was 77% and specificity 46%. Traditional criteria associated with long-term intubation included suspected smoke inhalation (OR 2.45 [95% CI, 1.18-5.11]), and singed facial hair (OR 2.53 [95% CI, 1.25-5.09]). The addition of these to ABA criteria created the Denver criteria, which exhibited an increased sensitivity for long-term intubations (95%), but decreased specificity (24%).
Intubation should be considered for patients displaying the Denver criteria, which includes full thickness facial burns, stridor, respiratory distress, swelling on laryngoscopy, upper airway trauma, altered mentation, hypoxia/hypercarbia, hemodynamic instability, suspected smoke inhalation, and singed facial hair. Patients lacking these criteria should not be intubated.
近期研究表明,烧伤患者正在接受不必要的插管。我们试图确定能预测插管有益的临床标准。
这是一项对2008 - 2013年因热烧伤入住本中心的成年插管患者的回顾性研究。插管标准定义为传统标准(疑似烟雾吸入、口咽烟灰、声音嘶哑、吞咽困难、面部毛发烧焦、口腔水肿、口腔烧伤、非全层面部烧伤),或2011年美国烧伤协会(ABA)指南定义的ABA标准(全层面部烧伤、喘鸣、呼吸窘迫、喉镜检查时肿胀、上呼吸道创伤、意识改变、低氧血症/高碳酸血症、血流动力学不稳定)。在28天内机械通气时间少于26天(无呼吸机天数(VFD))的患者被视为需要长期插管。VFD≥26天的患者被视为不必要的短期插管。
218例患者中,151例接受长期插管,67例接受短期插管。与传统标准(22.5%)相比,长期插管与ABA标准密切相关(77.5%)(p<0.001)。ABA标准对长期插管的敏感性为77%,特异性为46%。与长期插管相关的传统标准包括疑似烟雾吸入(比值比(OR)2.45 [95%可信区间(CI),1.18 - 5.11])和面部毛发烧焦(OR 2.53 [95% CI,1.25 - 5.09])。将这些标准加入ABA标准后形成了丹佛标准,该标准对长期插管的敏感性增加(95%),但特异性降低(24%)。
对于符合丹佛标准的患者应考虑插管,丹佛标准包括全层面部烧伤、喘鸣、呼吸窘迫、喉镜检查时肿胀、上呼吸道创伤、意识改变、低氧血症/高碳酸血症、血流动力学不稳定、疑似烟雾吸入和面部毛发烧焦。缺乏这些标准的患者不应插管。