Torssander J, Morfeldt-Månson L, Biberfeld G, Karlsson A, Putkonen P O, Wasserman J
Scand J Infect Dis. 1987;19(3):291-5. doi: 10.3109/00365548709018473.
The prevalence of oral colonization with Candida albicans was studied in 225 homosexual men, 99 of whom had HIV antibodies and in 175 heterosexual men. Oral candidal carriage was most prevalent among HIV seropositive homosexual men (77.8%). Rich growth of C. albicans in culture and findings of pseudomycelial elements in oral mucosal smear also correlated with HIV seropositivity. Pseudomycelial forms of C. albicans were demonstrated in mucosal smear from all patients with oral mucosal lesions suspected for candidiasis. However, 26/53 patients (49.1%) with positive smear had no clinical signs of oral candidiasis. The oral yeast flora was sampled twice in 85 homosexual men at an interval of 12-18 months. 71/85 patients (83.5%) were grouped into the same category of candidal colonization; carrier or noncarrier state, on both occasions. No statistically significant differences in numbers of CD 4 cells or CD 8 cells were observed between patients with respect to candidal colonization, when HIV seropositive and seronegative homosexual men were considered separately.
对225名男同性恋者和175名男异性恋者进行了白色念珠菌口腔定植患病率的研究，其中225名男同性恋者中有99人携带HIV抗体。口腔念珠菌携带情况在HIV血清阳性的男同性恋者中最为普遍（77.8%）。培养中白色念珠菌的丰富生长以及口腔黏膜涂片上假菌丝成分的发现也与HIV血清阳性相关。在所有疑似念珠菌病的口腔黏膜病变患者的黏膜涂片中均发现了白色念珠菌的假菌丝形式。然而，涂片阳性的53名患者中有26名（49.1%）没有口腔念珠菌病的临床症状。对85名男同性恋者的口腔酵母菌菌群进行了两次采样，间隔时间为12至18个月。85名患者中有71名（83.5%）在两次采样时都被归为同一类念珠菌定植类别，即携带者或非携带者状态。当分别考虑HIV血清阳性和血清阴性的男同性恋者时，在念珠菌定植方面，患者之间的CD4细胞或CD8细胞数量没有观察到统计学上的显著差异。
