Regional Centre for Child and Youth Mental Health, Uni Research Health, Uni Research, P.O. Box 7810, 5020 Bergen, Norway.
The Office for Children, Youth and Family Affairs, Region West, P.O. Box 2233, 3103 Tønsberg, Norway.
Nutrients. 2018 Apr 24;10(5):529. doi: 10.3390/nu10050529.
Docosahexaenoic acid (DHA, 22:6, -3) is a long-chain polyunsaturated fatty acid necessary for normal brain growth and cognitive development. Seafood and dietary supplements are the primary dietary sources of DHA. This study addresses the associations between DHA status in pregnant women and healthy, term-born infant problem-solving skills assessed using the Ages and Stages Questionnaire. The fatty acid status of maternal red blood cells (RBCs) was assessed in the 28th week of gestation and at three months postpartum. The infants’ fatty acid status (RBC) was assessed at three, six, and twelve months, and problem-solving skills were assessed at six and twelve months. Maternal DHA status in pregnancy was found to be positively associated with infants’ problem-solving skills at 12 months. This association remained significant even after controlling for the level of maternal education, a surrogate for socio-economic status. The infants’ DHA status at three months was associated with the infants’ problem solving at 12 months. The results accentuate the importance for pregnant and lactating women to have a satisfactory DHA status from dietary intake of seafood or other sources rich in DHA.
二十二碳六烯酸（DHA，22:6，-3）是一种长链多不饱和脂肪酸，对正常大脑生长和认知发育至关重要。海鲜和膳食补充剂是 DHA 的主要膳食来源。本研究旨在探讨孕妇 DHA 状况与采用年龄与阶段问卷评估的健康足月婴儿解决问题技能之间的关联。在妊娠 28 周和产后 3 个月评估母体红细胞（RBC）的脂肪酸状况。在 3、6 和 12 个月评估婴儿的脂肪酸状况（RBC），并在 6 和 12 个月评估解决问题的技能。发现孕妇怀孕期间的 DHA 状况与婴儿 12 个月时的解决问题技能呈正相关。即使在校正母体教育水平（社会经济地位的替代指标）后，这种关联仍然显著。婴儿 3 个月时的 DHA 状况与婴儿 12 个月时的解决问题能力相关。这些结果强调了孕妇和哺乳期妇女从富含 DHA 的海鲜或其他来源摄入足够的 DHA 对其自身及婴儿的重要性。
