Kimoto-Nira Hiromi
NARO Institute of Livestock and Grassland Science, Tsukuba, Ibaraki, Japan.
Anim Sci J. 2018 Jun;89(6):835-842. doi: 10.1111/asj.13017. Epub 2018 Apr 26.
Lactic acid bacteria play an essential role in the food industry in the manufacture of many fermented products (cheese, yogurt, fermented vegetables, etc.). Application of these organisms is now being extended to the area of health improvement, as their probiotic activities become known. Probiotics are defined as viable microorganisms that exert a beneficial effect on the health of the host when they are ingested in sufficient quantity. Lactic acid bacteria and bifidobacteria isolated from the human intestine are the most common probiotics used for human consumption. The development of new probiotics with new beneficial effects is eagerly awaited in the food industry. This review introduces Lactococcus, which are one of the genera of lactic acid bacteria and are mainly isolated from dairy products and fermented vegetables, as new probiotics, focusing especially on Lactococcus lactis H61, which improves skin status in Japanese women with oral intake of heat-killed or live cells. The deduced mechanisms associated with the beneficial effects of strain H61 are also discussed.
乳酸菌在食品工业中对许多发酵产品（奶酪、酸奶、发酵蔬菜等）的制造起着至关重要的作用。随着这些微生物的益生菌活性为人所知，它们的应用现在正扩展到健康改善领域。益生菌被定义为当摄入足够数量时对宿主健康产生有益影响的活微生物。从人类肠道分离出的乳酸菌和双歧杆菌是用于人类消费的最常见益生菌。食品工业急切期待开发具有新有益效果的新型益生菌。本综述介绍了乳酸杆菌属之一的乳球菌，其主要从乳制品和发酵蔬菜中分离得到，作为新型益生菌，特别关注乳酸乳球菌H61，口服热灭活或活细胞可改善日本女性的皮肤状况。还讨论了与菌株H61有益效果相关的推导机制。
