Tanaka Hirofumi
Cardiovascular Aging Research Laboratory, Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, TX, USA.
Pulse (Basel). 2018 Mar;5(1-4):1-6. doi: 10.1159/000461594. Epub 2017 Apr 7.
Arterial stiffness is an independent risk factor for cardiovascular disease. There are a number of techniques and devices that have been developed and utilized to capture the information pertaining to the elasticity of the blood vessel. Almost all the available indices of arterial stiffness are known to increase with advancing age and are elevated in the presence of hypertension and coronary heart disease. It is not known how closely these different measures of arterial stiffness are related to each other. Available evidence indicates that arterial stiffness indices that share a homogeneous methodology appear to demonstrate good correlations. However, there are no significant associations between some measures. These overall results may be surprising considering that all the indices are supposed to reflect the same property of the arterial wall (i.e., arterial elasticity). Interestingly, no or weak correlations between indices of vascular function are not confined only to arterial stiffness and can be extended to endothelial function and vascular reactivity measures.
动脉僵硬度是心血管疾病的独立危险因素。已经开发并使用了许多技术和设备来获取与血管弹性相关的信息。几乎所有现有的动脉僵硬度指标都已知会随着年龄的增长而增加，并且在高血压和冠心病患者中会升高。目前尚不清楚这些不同的动脉僵硬度测量方法之间的关联程度有多紧密。现有证据表明，采用相同方法的动脉僵硬度指标似乎具有良好的相关性。然而，一些测量方法之间并没有显著关联。考虑到所有指标都应该反映动脉壁的相同特性（即动脉弹性），这些总体结果可能会令人惊讶。有趣的是，血管功能指标之间无相关性或弱相关性不仅限于动脉僵硬度，还可以扩展到内皮功能和血管反应性测量。
