Sharma Reena K, Sharma Anjna K, Sharma Anuj
Department of Dermatology, Regional Hospital, Bilaspur, Himachal Pradesh, India.
Department of Radiodiagnos, Regional Hospital, Bilaspur, Himachal Pradesh, India.
Indian Dermatol Online J. 2018 May-Jun;9(3):185-187. doi: 10.4103/idoj.IDOJ_201_17.
Silicosis is an inflammatory disease of the lung characterized by irreversible lung fibrosis which develops from prolonged pulmonary inhalation and retention of crystalline silica and immune reaction. It mainly appears as an occupational hazard in persons involved in stone-quarrying, mining, and sand blasting. Crystalline silica is not only known to be responsible for silicosis but also for other autoimmune diseases including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA)-Caplan syndrome, systemic sclerosis (SSc), and antineutrophil cytoplasmic antibody (ANCA)-related vasculitis. Erasmus syndrome is the association of silica exposure and subsequent development of SSc. The limited numbers of cases reported in the literature were miners and only sporadically involved in other professionals. Here, we report a case of a 52 -year-old stone cutter who developed silicosis and SSc after 25 years of exposure.
矽肺是一种肺部炎症性疾病，其特征为不可逆的肺纤维化，由长期经肺吸入并留存结晶硅石以及免疫反应所致。它主要表现为从事采石、采矿和喷砂工作的人员所面临的职业危害。结晶硅石不仅被认为是矽肺的病因，还与包括系统性红斑狼疮（SLE）、类风湿关节炎（RA）-卡普兰综合征、系统性硬化症（SSc）以及抗中性粒细胞胞浆抗体（ANCA）相关血管炎在内的其他自身免疫性疾病有关。伊拉斯谟综合征是指接触硅石后继而发生系统性硬化症。文献中报道的病例数量有限，患者均为矿工，仅有零星病例涉及其他职业。在此，我们报告一例52岁的石匠病例，其在接触硅石25年后患上了矽肺和系统性硬化症。
