Institute of Electronic and Sensory Materials, Faculty of Materials Science and Materials Technology, Technological University Freiberg, Akademie Str. 6, 09599 Freiberg, Germany.
Biosensors (Basel). 2018 Jun 11;8(2):54. doi: 10.3390/bios8020054.
Antibiotic resistance and, accordingly, their pollution because of uncontrolled usage has emerged as a serious problem in recent years. Hence, there is an increased demand to develop robust, easy, and sensitive methods for rapid evaluation of antibiotics and their residues. Among different analytical methods, the aptamer-based biosensors (aptasensors) have attracted considerable attention because of good selectivity, specificity, and sensitivity. This review gives an overview about recently-developed aptasensors for antibiotic detection. The use of various aptamer assays to determine different groups of antibiotics, like β-lactams, aminoglycosides, anthracyclines, chloramphenicol, (fluoro)quinolones, lincosamide, tetracyclines, and sulfonamides are presented in this paper.
近年来，抗生素耐药性及其因滥用而造成的污染已成为一个严重的问题。因此，人们越来越需要开发强大、简单、灵敏的方法来快速评估抗生素及其残留。在各种分析方法中，基于适配体的生物传感器（aptasensor）因其良好的选择性、特异性和灵敏度而引起了广泛关注。本文综述了近年来用于抗生素检测的适配体传感器。本文介绍了各种适配体检测方法用于检测不同类型的抗生素，如β-内酰胺类、氨基糖苷类、蒽环类、氯霉素、（氟）喹诺酮类、林可酰胺类、四环素类和磺胺类。
