Erbb基因与小鼠11号染色体上的α-珠蛋白基因座相连。
Erbb is linked to the alpha-globin locus on mouse chromosome 11.
作者信息
Silver J, Whitney J B, Kozak C, Hollis G, Kirsch I
出版信息
Mol Cell Biol. 1985 Jul;5(7):1784-6. doi: 10.1128/mcb.5.7.1784-1786.1985.
Abstract
A fragment of the human gene for c-erb-B was used to map homologous sequences in mice. Analysis of somatic cell hybrids and recombinant inbred and congenic mouse strains indicated that this gene, designated Erbb, is closely linked to the gene for alpha-globin on mouse chromosome 11. Several genes controlling hematopoietic differentiation map to mouse chromosome 11.
摘要
人类c-erb-B基因的一个片段被用于在小鼠中定位同源序列。对体细胞杂种以及重组近交系和同源近交系小鼠品系的分析表明，这个被命名为Erbb的基因与小鼠11号染色体上的α-珠蛋白基因紧密连锁。几个控制造血分化的基因定位于小鼠11号染色体。
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