人类、小鼠和家猫中细胞rel序列的比较遗传图谱。

Brownell E, Kozak C A, Fowle J R, Modi W S, Rice N R, O'Brien S J

Am J Hum Genet. 1986 Aug;39(2):194-202.

We used in situ hybridization techniques to assign the human c-rel locus to the centromere-proximal portion of the short arm of chromosome 2 (2cent-2p13). We also determined the chromosomal location of c-rel sequences in the domestic cat and the laboratory mouse by using a human c-rel fragment to screen panels of rodent X cat and hamster X mouse somatic cell hybrid DNAs. The c-rel locus apparently maintains similar syntenic relationships with other known genetic markers in the human and cat, but displays different linkage relationships in the mouse.

我们运用原位杂交技术将人类c-rel基因座定位到染色体2短臂的着丝粒近端部分（2cen-2p13）。我们还通过使用人类c-rel片段筛选啮齿动物X猫和仓鼠X小鼠体细胞杂交DNA文库，确定了家猫和实验小鼠中c-rel序列的染色体定位。c-rel基因座在人类和猫中显然与其他已知遗传标记保持着相似的同线关系，但在小鼠中显示出不同的连锁关系。