具有抗炎活性的生物碱。 （原英文表述不太完整规范，推测完整意思是从某种植物等来源中提取的具有抗炎活性的生物碱，这里按照字面意思翻译）
Alkaloids from with anti-inflammatory activity.
作者信息
Yu Jin-Qian, Sun Xiao-Wei, Wang Zhi-Wei, Fang Lei, Wang Xiao
机构信息
a Shandong Key Laboratory of TCM Quality Control Technology, Shandong Analysis and Test Center , Qilu University of Technology (Shandong Academy of Sciences) , Jinan 250014 , China.
b School of Chemistry and Pharmaceutical Engineering , Qilu University of Technology , Jinan 250014 , China.
出版信息
J Asian Nat Prod Res. 2019 Aug;21(8):820-825. doi: 10.1080/10286020.2018.1482878. Epub 2018 Jun 22.
One new quinolinic scandine-type monoterpeniod alkaloid, 3-oxo-scandine (), as well as seven known ones (), was isolated from the roots of . Their structures were elucidated by extensive spectroscopic analysis. All of the compounds were prepared and evaluated for their anti-inflammatory activities by measuring the inhibitory activity of nitric oxide (NO) in RAW 264.7 mouse peritoneal macrophages. Compounds and showed significant activities with IC values of 8.54 and 5.19 μM, respectively.
从[植物名称]的根中分离出一种新的喹啉型山梗菜碱类单萜生物碱3-氧代山梗菜碱（）以及七种已知生物碱（）。通过广泛的光谱分析阐明了它们的结构。通过测量RAW 264.7小鼠腹腔巨噬细胞中一氧化氮（NO）的抑制活性，制备并评估了所有化合物的抗炎活性。化合物[具体化合物1]和[具体化合物2]表现出显著活性，IC50值分别为8.54和5.19 μM。
Zotero 插件