Department of Neuropsychology, kbo-Inn-Salzach-Klinikum, Psychiatric Hospital, Gabersee 13, 83512, Wasserburg am Inn, Germany.
Department of Psychiatry and Psychotherapy, University Hospital Jena, Jena, Germany.
Eur Arch Psychiatry Clin Neurosci. 2019 Aug;269(5):555-563. doi: 10.1007/s00406-018-0916-0. Epub 2018 Jun 27.
Physical activity is a common adjunctive therapy in psychiatric and psychosomatic hospitals. In the present study, we assessed the effects of an exercise program, integrated into routine inpatient treatment, on cognitive performance and subjective severity of depression in a sample of patients suffering from major depression. We randomized n = 38 patients with unipolar depression to either physical exercise (n = 18) or occupational therapy as an active control treatment (n = 20). Both treatments were delivered in group format over a period of 3-4 weeks. Data indicate that there were significant improvements of cognitive functions and depressive symptoms in both groups, with specific treatment effects in reaction time and in short-term verbal memory favoring the physical activity group. In conclusion, we found physical exercise to be a feasible, easy-to-implement add-on therapy for depressive patients with promising effects on cognitive performance. However, these results need to be replicated in larger samples with an extended follow-up.
身体活动是精神科和心身医学医院常用的辅助治疗方法。在本研究中，我们评估了将运动方案纳入常规住院治疗对患有重度抑郁症的患者认知表现和抑郁主观严重程度的影响。我们将 38 名患有单相抑郁的患者随机分为身体运动组（n = 18）或职业治疗组（n = 20）作为主动对照治疗。两种治疗均在 3-4 周内以小组形式进行。数据表明，两组患者的认知功能和抑郁症状均有显著改善，身体活动组在反应时间和短期言语记忆方面的特定治疗效果更好。总之，我们发现身体运动对于有认知障碍的抑郁患者是一种可行的、易于实施的附加治疗方法，对认知表现有积极影响。然而，这些结果需要在更大的样本和更长的随访中进行复制。
