Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA.
Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.
Curr Nutr Rep. 2018 Dec;7(4):310-323. doi: 10.1007/s13668-018-0242-1.
Obesity continues to be a growing concern globally due to association with a number of comorbidities and contributing significantly to increase in health care expenditures. Despite availability of a number of treatment modalities, lifestyle modification with dietary modification and exercise continues to be the foundation. However, the standard model of lifestyle modification is not efficacious or sustainable for many patients leading them to seek alternative approaches. We conducted a comprehensive literature review to present the data regarding efficacy and sustainability of many common dietary approaches.
Building upon previous work, recent randomized controlled trials have compared many popular diets head to head in varying patient populations. Along with the weight changes, studies have investigated the changes in metabolic parameters, inflammatory markers, and cardiac risk factor reduction. Though the studies do not show superiority of one diet compared to the other, the preventive benefits and other favorable metabolic changes of the diets make them worthy of consideration.
肥胖与多种合并症相关,且显著增加医疗保健支出,因此在全球范围内,肥胖仍是一个日益严重的问题。尽管有多种治疗方法,但饮食和运动的生活方式改变仍然是基础。然而,对于许多患者来说,标准的生活方式改变模式并不有效或可持续,导致他们寻求替代方法。我们进行了全面的文献综述,以介绍许多常见饮食方法的疗效和可持续性数据。
在以前工作的基础上,最近的随机对照试验在不同的患者群体中对头对头比较了许多流行的饮食方法。除了体重变化外,这些研究还调查了代谢参数、炎症标志物和心脏危险因素减少的变化。尽管这些研究并没有显示出一种饮食方法比另一种更优越,但这些饮食方法的预防益处和其他有利的代谢变化使其值得考虑。