del Palacio Hernanz A, Frias-Iniesta J, Gonzalez-Valle O, Borgers M, van Cutsem J, Cauwenbergh G
Br J Dermatol. 1986 Aug;115(2):217-25. doi: 10.1111/j.1365-2133.1986.tb05721.x.
The efficacy of itraconazole was assessed in an open trial in 30 patients with disseminated lesions of pityriasis versicolor confirmed by direct microscopy. The patients were allocated randomly to one of two treatment regimens, 200 mg once daily for 5 days or 100 mg once daily for 10 days. On assessment 3 weeks after the end of the treatment, 25 patients were healed, two patients had mild residual lesions, two had considerable residual lesions and one patient had relapsed. One patient reported dyspepsia and one patient reported stomach ache. One patient had asymptomatic elevation of serum transaminase (GOT and GPT) but this had returned to normal 3 weeks after the end of therapy.
在一项开放性试验中，对30例经直接显微镜检查确诊为播散性花斑癣的患者评估了伊曲康唑的疗效。患者被随机分配到两种治疗方案之一，即每日一次服用200mg，共5天，或每日一次服用100mg，共10天。在治疗结束3周后进行评估时，25例患者痊愈，2例患者有轻度残留病灶，2例有相当程度的残留病灶，1例患者复发。1例患者报告有消化不良，1例患者报告有胃痛。1例患者血清转氨酶（谷草转氨酶和谷丙转氨酶）无症状升高，但在治疗结束3周后已恢复正常。
