Bakry Ahmed Samir, Abbassy Mona Aly, Alharkan Hanin Fahad, Basuhail Sara, Al-Ghamdi Khalil, Hill Robert
Operative Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Conservative Dentistry Department, Faculty of Dentistry, Alexandria University, Alexandria 21614, Egypt.
Materials (Basel). 2018 Sep 6;11(9):1636. doi: 10.3390/ma11091636.
White-spot-lesions (WSL) are a common complication associated with orthodontic treatment. In the current study, the remineralization efficacy of a BiominF paste was compared to the efficacy of a fluoride gel.
Orthodontic brackets were bonded to 60 human premolars buccal surfaces, which were covered with varnish, except a small treatment area (3 mm²). All specimens were challenged by a demineralization solution for 4 days. Specimens were assigned into 4 groups: BiominF paste, Fluoride (4-min application), fluoride (twenty four hours application), and the control ( = 15). After cross-sectioning, enamel slabs having a thickness of approximately 100⁻120 μm were obtained. A TMR (Transverse Micro Radiography) technique was used to observe the sub-surface enamel lesions' depth and mineral density, and their response to the remineralization protocols. One way ANOVA was used to analyze the results (α = 0.05). The top and the cross-sectional surfaces were observed using SEM/EDS.
Specimens treated with BiominF paste showed significant decrease in delta z values, however lesion depth showed no significant difference when compared to the other three groups ( < 0.05). SEM/EDS observation showed the formation of crystal like structures on top of enamel demineralized surfaces, when treated with BiominF paste. In conclusion BiominF paste can be considered an effective remineralizing agent for white spot Lesions.
白斑病变（WSL）是正畸治疗常见的并发症。在本研究中，比较了BiominF糊剂与氟凝胶的再矿化效果。
将正畸托槽粘结到60颗人类前磨牙的颊面，除一个小的治疗区域（3平方毫米）外，其余均涂有清漆。所有标本用脱矿溶液处理4天。标本分为4组：BiominF糊剂组、氟化物（涂抹4分钟）组、氟化物（涂抹24小时）组和对照组（每组15个）。切片后，获得厚度约为100 - 120μm的釉质片。采用横向显微放射照相（TMR）技术观察釉质表层下病变的深度和矿物质密度，以及它们对再矿化方案的反应。采用单因素方差分析对结果进行分析（α = 0.05）。使用扫描电子显微镜/能谱仪（SEM/EDS）观察顶面和横截面。
用BiominF糊剂处理的标本的Δz值显著降低，但与其他三组相比，病变深度无显著差异（P < 0.05）。SEM/EDS观察显示，用BiominF糊剂处理时，釉质脱矿表面顶部形成了晶体状结构。总之，BiominF糊剂可被认为是治疗白斑病变的有效再矿化剂。
