睡眠与帕金森病
Sleep and Parkinson Disease.
作者信息
Bollu Pradeep C, Sahota Pradeep
机构信息
Pradeep C. Bollu, MD, MSMA member since 2003, in the Department of Neurology, University of Missouri School of Medicine.
Pradeep Sahota, MD, FAAN, MSMA member since 2003, in the Department of Neurology, University of Missouri School of Medicine.
出版信息
Mo Med. 2017 Sep-Oct;114(5):381-386.
Abstract
Sleep disorders are prevalent in Parkinson disease (PD), a disease with well recognized motor dysfunction. Sleep related problems received little attention until the last three decades. Sleep disorders seen in PD patients include insomnia, excessive sleepiness, restless legs syndrome, REM sleep behavior disorder. Some of these can have significant impact and lower the quality of life in these patients. An understanding of sleep issues in PD can help identify them early and result in optimal management.
摘要
睡眠障碍在帕金森病（PD）中很常见，这是一种运动功能障碍已得到充分认识的疾病。直到过去三十年，与睡眠相关的问题才受到较少关注。帕金森病患者出现的睡眠障碍包括失眠、过度嗜睡、不宁腿综合征、快速眼动睡眠行为障碍。其中一些睡眠障碍会产生重大影响并降低这些患者的生活质量。了解帕金森病中的睡眠问题有助于早期识别它们并实现最佳管理。
相似文献
1
Sleep and Parkinson Disease.睡眠与帕金森病
Mo Med. 2017 Sep-Oct;114(5):381-386.
2
Effects of sleep disorders on the non-motor symptoms of Parkinson disease.睡眠障碍对帕金森病非运动症状的影响。
J Clin Sleep Med. 2013 Nov 15;9(11):1119-29. doi: 10.5664/jcsm.3148.
3
An overview of sleep and circadian dysfunction in Parkinson's disease.帕金森病睡眠与昼夜节律紊乱概述。
J Sleep Res. 2018 Jun;27(3):e12673. doi: 10.1111/jsr.12673. Epub 2018 Mar 1.
4
Neurodegenerative Disorders and Sleep.神经退行性疾病与睡眠
Sleep Med Clin. 2018 Mar;13(1):63-70. doi: 10.1016/j.jsmc.2017.09.006. Epub 2017 Nov 10.
5
Sleep disturbances and excessive daytime sleepiness in Parkinson disease: an overview.帕金森病中的睡眠障碍与日间过度嗜睡：综述
J Neural Transm Suppl. 2006(70):349-55. doi: 10.1007/978-3-211-45295-0_53.
6
Management Recommendations on Sleep Disturbance of Patients with Parkinson's Disease.帕金森病患者睡眠障碍的管理建议
Chin Med J (Engl). 2018 Dec 20;131(24):2976-2985. doi: 10.4103/0366-6999.247210.
7
Sleep Disorders and Future Diagnosis of Parkinsonism: A Prospective Study Using the Canadian Longitudinal Study on Aging.睡眠障碍与帕金森病的未来诊断：一项基于加拿大衰老纵向研究的前瞻性研究
J Parkinsons Dis. 2022;12(1):257-266. doi: 10.3233/JPD-212796.
8
Sleep disorders in Parkinson's disease.帕金森病中的睡眠障碍
Clin Cornerstone. 2004;6 Suppl 1A:S7-15. doi: 10.1016/s1098-3597(04)90013-0.
9
The underdiagnosis of sleep disorders in patients with multiple sclerosis.多发性硬化症患者睡眠障碍的诊断不足。
J Clin Sleep Med. 2014 Sep 15;10(9):1025-31. doi: 10.5664/jcsm.4044.
10
[Sleep disorders in Parkinson's disease: REM sleep behaviour disorder and restless legs syndrome].帕金森病中的睡眠障碍：快速眼动睡眠行为障碍和不宁腿综合征
Rev Neurol. 2010 Feb 8;50 Suppl 2:S15-9.
引用本文的文献
1
Prevalence and associations of self-reported sleep problems in a large sample of patients with Parkinson's disease.大量帕金森病患者样本中自我报告的睡眠问题的患病率及相关性
J Sleep Res. 2025 Aug;34(4):e14453. doi: 10.1111/jsr.14453. Epub 2025 Jan 19.
2
Insomnia in Parkinson's Disease: Causes, Consequences, and Therapeutic Approaches.帕金森病中的失眠：病因、后果及治疗方法
Mol Neurobiol. 2025 Feb;62(2):2292-2313. doi: 10.1007/s12035-024-04400-4. Epub 2024 Aug 5.
3
Contributions of Basal Ganglia Circuits to Perception, Attention, and Consciousness.基底神经节回路对感知、注意和意识的贡献。
J Cogn Neurosci. 2024 Jul 1;36(8):1620-1642. doi: 10.1162/jocn_a_02177.
4
REM Sleep Loss-Induced Elevated Noradrenaline Plays a Significant Role in Neurodegeneration: Synthesis of Findings to Propose a Possible Mechanism of Action from Molecule to Patho-Physiological Changes.快速眼动睡眠剥夺诱导的去甲肾上腺素升高在神经退行性变中起重要作用：综合研究结果提出从分子到病理生理变化的可能作用机制
Brain Sci. 2023 Dec 21;14(1):8. doi: 10.3390/brainsci14010008.
5
Evaluation of Nocturnal Symptoms in Chinese Parkinson's Disease Patients Based on the PDSS-2 Scale: A Multicenter Cross-Sectional Study.基于 PDSS-2 量表评估中国帕金森病患者的夜间症状：一项多中心横断面研究。
J Parkinsons Dis. 2023;13(6):1061-1071. doi: 10.3233/JPD-230060.
6
Cortical excitability in patients with REM sleep behavior disorder with abnormal TRODAT-1 SPECT scan: an insight into prodromal Parkinson's disease.快速眼动睡眠行为障碍患者且TRODAT-1单光子发射计算机断层扫描异常时的皮质兴奋性：对帕金森病前驱期的见解
Front Neurol. 2023 May 24;14:1156041. doi: 10.3389/fneur.2023.1156041. eCollection 2023.
7
The Correlation Between Parkinson's Disease and Rapid Eye Movement Sleep Behavior Disorder: A Systematic Review.帕金森病与快速眼动睡眠行为障碍之间的相关性：一项系统综述。
Cureus. 2021 Aug 9;13(8):e17026. doi: 10.7759/cureus.17026. eCollection 2021 Aug.
8
Spectrum of Non-Motor Symptoms in Parkinson's Disease.帕金森病的非运动症状谱
Cureus. 2021 Feb 11;13(2):e13275. doi: 10.7759/cureus.13275.
9
Aging-associated alterations in epidermal function and their clinical significance.衰老相关的表皮功能改变及其临床意义。
Aging (Albany NY). 2020 Mar 27;12(6):5551-5565. doi: 10.18632/aging.102946.
10
The related factors of sleep benefit in Parkinson's disease: A systematic review and meta-analysis.帕金森病睡眠获益的相关因素：系统评价和荟萃分析。
PLoS One. 2019 Mar 11;14(3):e0212951. doi: 10.1371/journal.pone.0212951. eCollection 2019.
本文引用的文献
1
Restless legs syndrome in patients with Parkinson's disease: a comparative study on prevalence, clinical characteristics, quality of life and nutritional status.帕金森病患者的不安腿综合征：患病率、临床特征、生活质量和营养状况的比较研究
Acta Neurol Scand. 2015 Apr;131(4):211-8. doi: 10.1111/ane.12307. Epub 2014 Sep 28.
2
The impact of non-motor symptoms on health-related quality of life of patients with Parkinson's disease.帕金森病患者非运动症状对健康相关生活质量的影响。
Mov Disord. 2011 Feb 15;26(3):399-406. doi: 10.1002/mds.23462. Epub 2011 Jan 24.
3
Phasic muscle activity in sleep and clinical features of Parkinson disease.睡眠中的阶段性肌肉活动与帕金森病的临床特征。
Ann Neurol. 2010 Sep;68(3):353-9. doi: 10.1002/ana.22076.
4
Fatigue and excessive daytime sleepiness in idiopathic Parkinson's disease differently correlate with motor symptoms, depression and dopaminergic treatment.特发性帕金森病的疲劳和日间过度嗜睡与运动症状、抑郁和多巴胺能治疗有不同的相关性。
Eur J Neurol. 2010 Dec;17(12):1428-36. doi: 10.1111/j.1468-1331.2010.03063.x.
5
Frequency of dementia, depression, and other neuropsychiatric symptoms in 1,449 outpatients with Parkinson's disease.1449 例帕金森病门诊患者的痴呆、抑郁和其他神经精神症状的频率。
J Neurol. 2010 Jul;257(7):1073-82. doi: 10.1007/s00415-010-5465-z. Epub 2010 Feb 6.
6
Sleepiness in Parkinson's disease.帕金森病中的嗜睡。
Parkinsonism Relat Disord. 2009 Dec;15 Suppl 3:S101-4. doi: 10.1016/S1353-8020(09)70792-8.
7
Potentially lethal behaviors associated with rapid eye movement sleep behavior disorder: review of the literature and forensic implications.与快速眼动睡眠行为障碍相关的潜在致命行为：文献综述及法医学意义
J Forensic Sci. 2009 Nov;54(6):1475-84. doi: 10.1111/j.1556-4029.2009.01163.x. Epub 2009 Sep 25.
8
Mild cognitive impairment in rapid eye movement sleep behavior disorder and Parkinson's disease.快速眼动睡眠行为障碍与帕金森病中的轻度认知障碍
Ann Neurol. 2009 Jul;66(1):39-47. doi: 10.1002/ana.21680.
9
Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder.量化特发性快速眼动睡眠行为障碍中神经退行性疾病的风险。
Neurology. 2009 Apr 14;72(15):1296-300. doi: 10.1212/01.wnl.0000340980.19702.6e. Epub 2008 Dec 24.
10
A review of normal sleep and its disturbances in Parkinson's disease.帕金森病患者正常睡眠及其障碍的综述。
Parkinsonism Relat Disord. 1999 Apr;5(1-2):1-17. doi: 10.1016/s1353-8020(99)00011-5.
Zotero 插件