Skoczyńska Marta, Świerkot Jerzy
Department and Clinic of Rheumatology and Internal Medicine, Wrocław Medical Hospital, Wrocław Medical University, Poland.
Reumatologia. 2018;56(4):259-267. doi: 10.5114/reum.2018.77979. Epub 2018 Aug 31.
Rheumatoid arthritis (RA) is a systemic connective tissue disease which develops in the course of an autoimmune inflammatory process triggered by environmental factors in a genetically predisposed person. One of the environmental factors is the diet. RA patients' adherence to a healthy diet remains low, despite plentiful data confirming positive effects of some foods, e.g. fish rich in n-3 polyunsaturated fatty acids (PUFAs), as well as the negative influence of unhealthy eating patterns, such as high consumption of fats and sugars, on RA incidence, activity and treatment response. In this review, we present current knowledge on the role of diet in rheumatoid arthritis, including dietary factors' preventive/promoting influence on RA development, as well as their impact on RA activity. We hope this article will aid and encourage clinicians to recommend a relevant dietary intervention to their RA patients.
类风湿关节炎(RA)是一种系统性结缔组织疾病,在遗传易感性个体中,由环境因素触发的自身免疫炎症过程中发展而来。环境因素之一是饮食。尽管有大量数据证实某些食物具有积极作用,例如富含n-3多不饱和脂肪酸(PUFA)的鱼类,以及不健康的饮食模式(如高脂肪和高糖摄入)对RA发病率、活动度和治疗反应的负面影响,但RA患者对健康饮食的依从性仍然很低。在本综述中,我们介绍了目前关于饮食在类风湿关节炎中的作用的知识,包括饮食因素对RA发展的预防/促进影响,以及它们对RA活动度的影响。我们希望本文将有助于并鼓励临床医生向他们的RA患者推荐相关的饮食干预措施。