新型环脂肽抗生素LY146032对革兰氏阳性临床细菌的体外活性
In vitro activity of a new cyclic lipopeptide antibiotic, LY146032, against gram-positive clinical bacteria.
作者信息
Huovinen P, Kotilainen P
出版信息
Antimicrob Agents Chemother. 1987 Mar;31(3):455-7. doi: 10.1128/AAC.31.3.455.
Abstract
The in vitro activity of LY146032, a novel cyclic lipopeptide antibiotic, was tested against different gram-positive clinical isolates. The activity of LY146032 was clearly higher than that of vancomycin against all isolates tested. However, in some instances rifampin and imipenem showed higher activity than did LY146032.
摘要
新型环脂肽抗生素LY146032的体外活性针对不同革兰氏阳性临床分离株进行了测试。LY146032对所有测试分离株的活性明显高于万古霉素。然而，在某些情况下，利福平和亚胺培南的活性高于LY146032。
相似文献
1
In vitro activity of a new cyclic lipopeptide antibiotic, LY146032, against gram-positive clinical bacteria.新型环脂肽抗生素LY146032对革兰氏阳性临床细菌的体外活性
Antimicrob Agents Chemother. 1987 Mar;31(3):455-7. doi: 10.1128/AAC.31.3.455.
2
Comparative in vitro activity of LY146032 (daptomycin), a new lipopeptide antimicrobial.新型脂肽类抗菌药物LY146032（达托霉素）的体外活性比较
Eur J Clin Microbiol. 1987 Feb;6(1):100-3. doi: 10.1007/BF02097211.
3
In vitro activity of LY146032 alone and in combination with other antibiotics against gram-positive bacteria.LY146032单独及与其他抗生素联合对革兰氏阳性菌的体外活性。
Antimicrob Agents Chemother. 1988 Feb;32(2):279-81. doi: 10.1128/AAC.32.2.279.
4
Comparative in-vitro activity of LY146032 a new peptolide, with vancomycin and eight other agents against gram-positive organisms.新型缩肽类抗生素LY146032与万古霉素及其他八种药物对革兰氏阳性菌的体外活性比较
J Antimicrob Chemother. 1987 Aug;20(2):191-6. doi: 10.1093/jac/20.2.191.
5
Comparative in-vitro activity of LY146032 and eight other antibiotics against gram-positive bacteria isolated from children.LY146032与其他八种抗生素对从儿童中分离出的革兰氏阳性菌的体外活性比较
J Antimicrob Chemother. 1987 Aug;20(2):203-7. doi: 10.1093/jac/20.2.203.
6
In vitro activity of LY146032, a new lipopeptide antibiotic, against gram-positive cocci.新型脂肽抗生素LY146032对革兰氏阳性球菌的体外活性
Antimicrob Agents Chemother. 1987 Feb;31(2):340-2. doi: 10.1128/AAC.31.2.340.
7
In-vitro susceptibility of gram-positive cocci to LY146032 teicoplanin, sodium fusidate, vancomycin, and rifampicin.革兰氏阳性球菌对LY146032、替考拉宁、夫西地酸钠、万古霉素和利福平的体外敏感性。
J Antimicrob Chemother. 1987 Aug;20(2):197-202. doi: 10.1093/jac/20.2.197.
8
In-vitro activity of LY146032 against gram-positive isolates from cancer patients.LY146032对癌症患者革兰氏阳性分离株的体外活性。
J Antimicrob Chemother. 1987 Oct;20(4):497-503. doi: 10.1093/jac/20.4.497.
9
In vitro activities of daptomycin (LY146032) and paldimycin (U-70,138F) against anaerobic gram-positive bacteria.达托霉素（LY146032）和帕地霉素（U-70,138F）对厌氧革兰氏阳性菌的体外活性。
Antimicrob Agents Chemother. 1988 May;32(5):788-90. doi: 10.1128/AAC.32.5.788.
10
In-vitro activity of LY146032 against Staphylococcus aureus, Listeria monocytogenes, Corynebacterium JK, and Bacillus spp., in comparison with various antibiotics.
J Antimicrob Chemother. 1987 Aug;20(2):209-12. doi: 10.1093/jac/20.2.209.
引用本文的文献
1
In vitro activities of daptomycin, vancomycin, quinupristin- dalfopristin, linezolid, and five other antimicrobials against 307 gram-positive anaerobic and 31 Corynebacterium clinical isolates.达托霉素、万古霉素、奎奴普丁-达福普汀、利奈唑胺及其他五种抗菌药物对307株革兰氏阳性厌氧菌和31株棒状杆菌临床分离株的体外活性。
Antimicrob Agents Chemother. 2003 Jan;47(1):337-41. doi: 10.1128/AAC.47.1.337-341.2003.
2
Pharmacodynamics of daptomycin in a murine thigh model of Staphylococcus aureus infection.达托霉素在金黄色葡萄球菌感染小鼠大腿模型中的药效学
Antimicrob Agents Chemother. 2001 Mar;45(3):845-51. doi: 10.1128/AAC.45.3.845-851.2001.
3
Identification of daptomycin-binding proteins in the membrane of Enterococcus hirae.迟缓埃希氏菌膜中达托霉素结合蛋白的鉴定
Antimicrob Agents Chemother. 1995 Sep;39(9):2068-72. doi: 10.1128/AAC.39.9.2068.
4
In vitro activities of daptomycin (LY146032) and paldimycin (U-70,138F) against anaerobic gram-positive bacteria.达托霉素（LY146032）和帕地霉素（U-70,138F）对厌氧革兰氏阳性菌的体外活性。
Antimicrob Agents Chemother. 1988 May;32(5):788-90. doi: 10.1128/AAC.32.5.788.
5
Early stages of in vitro killing curve of LY146032 and vancomycin for Staphylococcus aureus.LY146032和万古霉素对金黄色葡萄球菌的体外杀菌曲线早期阶段。
Antimicrob Agents Chemother. 1988 Apr;32(4):454-7. doi: 10.1128/AAC.32.4.454.
6
In vitro selection of bacteria resistant to LY146032, a new cyclic lipopeptide.对新型环脂肽LY146032具有抗性的细菌的体外筛选
Antimicrob Agents Chemother. 1988 Jan;32(1):24-6. doi: 10.1128/AAC.32.1.24.
7
Influence of daptomycin on staphylococcal abscesses and experimental tobramycin nephrotoxicity.达托霉素对葡萄球菌脓肿及实验性妥布霉素肾毒性的影响。
Antimicrob Agents Chemother. 1989 Aug;33(8):1280-5. doi: 10.1128/AAC.33.8.1280.
8
Treatment of chronic experimental Staphylococcus aureus osteomyelitis with LY146032 and vancomycin.LY146032与万古霉素治疗慢性实验性金黄色葡萄球菌骨髓炎
Eur J Clin Microbiol Infect Dis. 1989 Jun;8(6):562-3. doi: 10.1007/BF01967482.
9
Lipoteichoic acid as a new target for activity of antibiotics: mode of action of daptomycin (LY146032).脂磷壁酸作为抗生素活性的新靶点：达托霉素（LY146032）的作用模式。
Antimicrob Agents Chemother. 1990 Jun;34(6):1220-6. doi: 10.1128/AAC.34.6.1220.
10
In vitro activity of daptomycin-metronidazole combinations against mixed bacterial cultures: reduced activity of metronidazole against Bacteroides species in the presence of Enterococcus faecalis.达托霉素-甲硝唑联合用药对混合细菌培养物的体外活性：在粪肠球菌存在的情况下甲硝唑对拟杆菌属细菌的活性降低。
Eur J Clin Microbiol Infect Dis. 1990 Apr;9(4):287-91. doi: 10.1007/BF01968064.
本文引用的文献
1
Aminoglycoside resistance among blood culture isolates.血培养分离株中的氨基糖苷类耐药性。
J Clin Microbiol. 1984 Jul;20(1):65-9. doi: 10.1128/jcm.20.1.65-69.1984.
2
Adherence of slime-producing strains of Staphylococcus epidermidis to smooth surfaces.表皮葡萄球菌产黏液菌株对光滑表面的黏附
Infect Immun. 1982 Jul;37(1):318-26. doi: 10.1128/iai.37.1.318-326.1982.
3
In vitro activity and mechanism of action of A21978C1, a novel cyclic lipopeptide antibiotic.新型环脂肽抗生素A21978C1的体外活性及作用机制
Antimicrob Agents Chemother. 1985 Mar;27(3):357-62. doi: 10.1128/AAC.27.3.357.
4
Usefulness of a test for slime production as a marker for clinically significant infections with coagulase-negative staphylococci.检测黏液产生作为凝固酶阴性葡萄球菌临床显著感染标志物的效用。
J Infect Dis. 1986 Feb;153(2):332-9. doi: 10.1093/infdis/153.2.332.
5
Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia.由产毒素梭状芽孢杆菌引起的抗生素相关性假膜性结肠炎。
N Engl J Med. 1978 Mar 9;298(10):531-4. doi: 10.1056/NEJM197803092981003.
Zotero 插件