Occupational and Environmental Medicine, Department for Laboratory Medicine, Lund University, 221 85 Lund, Sweden.
Int J Environ Res Public Health. 2018 Oct 19;15(10):2294. doi: 10.3390/ijerph15102294.
Traffic-related air pollution could be a danger to the health of children. Earlier studies have linked prenatal exposure to an increased risk of a range of diseases and negative health outcomes, including overweight and obesity. Presently, a knowledge gap exists in investigating the risk of overweight and obesity among children exposed to lower levels of air pollution in utero. This study aimed to investigate the relationship between prenatal traffic-related air pollution (nitrogen dioxides (NO) and traffic density) and childhood overweight and obesity in Malmö, Sweden. A cohort, based on attendance of a four-year check-up examination at Swedish Child Health Care (CHC) centers, and a parent-assessed questionnaire provided data on body-mass index adjusted for four-year-old children (ISO-BMI) as well as socioeconomic and health variables. We estimated exposure by using traffic density and levels of NO at the maternal geocoded residential level. Analysis of 5815 children was performed using binary logistic regression models. This study showed no associations of increased risk for childhood overweight or obesity through to prenatal exposure to NO in this low-exposure setting. We further suggest analysis of risks related to exposure levels ranging between the ones presented here and those proposed in previous literature.
交通相关的空气污染可能对儿童的健康造成危害。早期的研究已经将产前暴露于一系列疾病和负面健康结果（包括超重和肥胖）的风险与交通相关的空气污染联系起来。目前，在调查儿童在子宫内暴露于较低水平的空气污染时超重和肥胖的风险方面存在知识空白。本研究旨在调查瑞典马尔默市产前交通相关空气污染（二氧化氮 (NO) 和交通密度）与儿童超重和肥胖之间的关系。该队列基于参加瑞典儿童保健中心 (CHC) 的四年一次的检查，以及父母评估的问卷，提供了关于儿童（ISO-BMI）的身体质量指数（BMI）调整数据，以及社会经济和健康变量。我们通过母亲地理编码的居住水平上的交通密度和 NO 水平来估计暴露情况。对 5815 名儿童进行了二元逻辑回归模型分析。本研究表明，在这种低暴露环境下，产前暴露于 NO 并不会增加儿童超重或肥胖的风险。我们进一步建议分析与本研究中提出的和之前文献中提出的暴露水平相关的风险。
