Bilirubin, a Cardiometabolic Signaling Molecule.
作者信息
Hinds Terry D, Stec David E
机构信息
From the Department of Physiology and Pharmacology, University of Toledo College of Medicine, OH (T.D.H.).
Department of Physiology and Biophysics, Mississippi Center for Obesity Research, University of Mississippi Medical Center, Jackson (D.E.S.).
出版信息
Hypertension. 2018 Oct;72(4):788-795. doi: 10.1161/HYPERTENSIONAHA.118.11130.
Abstract
摘要
相似文献
1
Bilirubin, a Cardiometabolic Signaling Molecule.
Hypertension. 2018 Oct;72(4):788-795. doi: 10.1161/HYPERTENSIONAHA.118.11130.
2
Bilirubin Safeguards Cardiorenal and Metabolic Diseases: a Protective Role in Health.
Curr Hypertens Rep. 2019 Oct 10;21(11):87. doi: 10.1007/s11906-019-0994-z.
3
mTOR Signaling in Cardiometabolic Disease, Cancer, and Aging.
Oxid Med Cell Longev. 2017;2017:6018675. doi: 10.1155/2017/6018675. Epub 2017 Jul 10.
4
Targeting Interferon Regulatory Factor for Cardiometabolic Diseases: Opportunities and Challenges.
Curr Drug Targets. 2017;18(15):1754-1778. doi: 10.2174/1389450116666150804110412.
5
Toll-like receptor signaling: common pathways that drive cardiovascular disease and rheumatoid arthritis.
Arthritis Care Res (Hoboken). 2011 Apr;63(4):500-11. doi: 10.1002/acr.20382.
6
Targeting Apelinergic System in Cardiometabolic Disease.
Curr Drug Targets. 2017;18(15):1785-1791. doi: 10.2174/1389450117666160613105152.
7
A Novel Perspective on the Biology of Bilirubin in Health and Disease.
Trends Mol Med. 2016 Sep;22(9):758-768. doi: 10.1016/j.molmed.2016.07.004. Epub 2016 Aug 8.
8
Fatty acids getting NAD+ about cardiometabolic diseases.
Curr Opin Lipidol. 2019 Dec;30(6):486-487. doi: 10.1097/MOL.0000000000000637.
9
Emerging therapeutic potential of glycine in cardiometabolic diseases: dual benefits in lipid and glucose metabolism.
Curr Opin Lipidol. 2018 Oct;29(5):428-432. doi: 10.1097/MOL.0000000000000543.
10
Reprogramming Interferon Regulatory Factor Signaling in Cardiometabolic Diseases.
Physiology (Bethesda). 2017 May;32(3):210-223. doi: 10.1152/physiol.00038.2016.
引用本文的文献
1
Bilirubin - new insights into an old molecule.
Biochem Med (Zagreb). 2025 Jun 15;35(2):020501. doi: 10.11613/BM.2025.020501. Epub 2025 Apr 15.
2
Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.
Nat Commun. 2025 May 28;16(1):4935. doi: 10.1038/s41467-025-59950-5.
3
Novel link between plasma bilirubin and anti-inflammatory miRNA profiles in follicular fluid of IVF patients.
Am J Physiol Endocrinol Metab. 2025 Jun 1;328(6):E1001-E1012. doi: 10.1152/ajpendo.00479.2024. Epub 2025 May 5.
4
The Protective Effect of Bilirubin on MAFLD May Be Mediated by Improving Insulin Re-Sistance and Alleviating Chronic Inflammation.
J Inflamm Res. 2025 Apr 24;18:5555-5572. doi: 10.2147/JIR.S520257. eCollection 2025.
5
Circulating Bilirubin Levels, but Not Their Genetic Determinants, Are Inversely Associated with Steatotic Liver Disease in Adolescents.
Int J Mol Sci. 2025 Mar 25;26(7):2980. doi: 10.3390/ijms26072980.
6
Advances in Nano-Immunomodulatory Systems for the Treatment of Acute Kidney Injury.
Adv Sci (Weinh). 2025 May;12(17):e2409190. doi: 10.1002/advs.202409190. Epub 2025 Mar 27.
7
Steroid receptors and coregulators: Dissemination of sex differences and emerging technologies.
J Biol Chem. 2025 Apr;301(4):108363. doi: 10.1016/j.jbc.2025.108363. Epub 2025 Feb 27.
8
Urobilin Derived from Bilirubin Bioconversion Binds Albumin and May Interfere with Bilirubin Interacting with Albumin: Implications for Disease Pathology.
Biomedicines. 2025 Jan 26;13(2):302. doi: 10.3390/biomedicines13020302.
9
Association of Trace Elements with Polycystic Ovary Syndrome in Women-A Case-Control Study.
Metabolites. 2025 Jan 29;15(2):79. doi: 10.3390/metabo15020079.
10
Influence of Functional Variations in Genes of Neurotrophins and Neurotransmitter Systems on the Development of Retinopathy of Prematurity.
Int J Mol Sci. 2025 Jan 22;26(3):898. doi: 10.3390/ijms26030898.
本文引用的文献
1
Loss of biliverdin reductase-A promotes lipid accumulation and lipotoxicity in mouse proximal tubule cells.
Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F323-F331. doi: 10.1152/ajprenal.00495.2017. Epub 2018 Apr 4.
2
Biliverdin reductase and bilirubin in hepatic disease.
Am J Physiol Gastrointest Liver Physiol. 2018 Jun 1;314(6):G668-G676. doi: 10.1152/ajpgi.00026.2018. Epub 2018 Mar 1.
3
Bilirubin in the Liver-Gut Signaling Axis.
Trends Endocrinol Metab. 2018 Mar;29(3):140-150. doi: 10.1016/j.tem.2018.01.002. Epub 2018 Feb 3.
4
Mild hyperbilirubinaemia as an endogenous mitigator of overweight and obesity: Implications for improved metabolic health.
Atherosclerosis. 2018 Feb;269:306-311. doi: 10.1016/j.atherosclerosis.2017.12.021. Epub 2017 Dec 14.
5
Absence of the biliverdin reductase-a gene is associated with increased endogenous oxidative stress.
Free Radic Biol Med. 2018 Feb 1;115:156-165. doi: 10.1016/j.freeradbiomed.2017.11.020. Epub 2017 Dec 1.
6
Relationship Between Total Serum Bilirubin Levels and Carotid and Femoral Atherosclerosis in Familial Dyslipidemia.
Arterioscler Thromb Vasc Biol. 2017 Dec;37(12):2356-2363. doi: 10.1161/ATVBAHA.117.310071. Epub 2017 Oct 26.
7
Bilirubin Decreases Macrophage Cholesterol Efflux and ATP-Binding Cassette Transporter A1 Protein Expression.
J Am Heart Assoc. 2017 Apr 28;6(5):e005520. doi: 10.1161/JAHA.117.005520.
8
Bilirubin and Stroke Risk Using a Mendelian Randomization Design.
Stroke. 2017 May;48(5):1154-1160. doi: 10.1161/STROKEAHA.116.015083. Epub 2017 Apr 7.
9
Bilirubin Prevents Atherosclerotic Lesion Formation in Low-Density Lipoprotein Receptor-Deficient Mice by Inhibiting Endothelial VCAM-1 and ICAM-1 Signaling.
J Am Heart Assoc. 2017 Apr 1;6(4):e004820. doi: 10.1161/JAHA.116.004820.
10
Chronically elevated bilirubin protects from cardiac reperfusion injury in the male Gunn rat.
Acta Physiol (Oxf). 2017 Aug;220(4):461-470. doi: 10.1111/apha.12858. Epub 2017 Mar 14.
Zotero 插件