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分子方法在中草药成分鉴定中的应用。

Application of Molecular Methods in the Identification of Ingredients in Chinese Herbal Medicines.

机构信息

School of Computer and Information Engineering, Harbin University of Commerce, Harbin 150028, China.

Life sciences and Environmental Sciences Development Center, Harbin University of Commerce, Harbin 150010, China.

出版信息

Molecules. 2018 Oct 22;23(10):2728. doi: 10.3390/molecules23102728.

Abstract

There are several kinds of Chinese herbal medicines originating from diverse sources. However, the rapid taxonomic identification of large quantities of Chinese herbal medicines is difficult using traditional methods, and the process of identification itself is prone to error. Therefore, the traditional methods of Chinese herbal medicine identification must meet higher standards of accuracy. With the rapid development of bioinformatics, methods relying on bioinformatics strategies offer advantages with respect to the speed and accuracy of the identification of Chinese herbal medicine ingredients. This article reviews the applicability and limitations of biochip and DNA barcoding technology in the identification of Chinese herbal medicines. Furthermore, the future development of the two technologies of interest is discussed.

摘要

中药材有多种来源。然而,传统方法难以对大量中药材进行快速的分类鉴定,而且鉴定过程本身容易出错。因此,中药材鉴定的传统方法必须达到更高的准确性标准。随着生物信息学的快速发展,基于生物信息学策略的方法在中药材成分鉴定的速度和准确性方面具有优势。本文综述了生物芯片和 DNA 条形码技术在中药材鉴定中的适用性和局限性。此外,还讨论了这两种技术的未来发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3bd/6222746/9f9a071ab891/molecules-23-02728-g001.jpg

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